| Representative[2] | Party | Years | District home | Note |
|---|
| Richard Thomas | Federalist | 1791 – 1793 | | U.S. Representative from Pennsylvania from 1795 to 1801[3] |
| William Ross | Democratic-Republican | 1811 – 1815 | | |
| Charles Fraser | Democratic-Republican | 1815 – 1819 | | |
| Simon Snyder | Democratic-Republican | 1817 – 1819 | | 3rd Governor of Pennsylvania from 1808 to 1817[4] |
| Robert Willets | Democratic | 1819 – 1821 | | |
| Redmond Conyngham | Federalist | 1819 – 1823 | | |
| Andrew Albright | Republican | 1821 – 1822 | | |
| Lewis Dewart | Democratic-Republican | 1821 – 1825 | | |
| John Ray | Jackson Democrat | 1827 – 1829 | | |
| Samuel Jones Packer | Anti-Mason | 1831 – 1833 | | |
| Isaac Slenker | Democratic | 1835 – 1837 | | |
| Charles Frailey | Democratic | 1835 – 1841 | | |
| Samuel Freeman Headley | Democratic | 1841 – 1842 | | |
| Jefferson Kreider Heckman | Democratic | 1843 – 1845 | | |
| Jacob D. Boas | Whig | 1847 – 1849 | | |
| Conrad Schilp Shimer | Democratic | 1851 – 1852 | | |
| William Fry | Democratic | 1853 – 1854 | | |
| Joseph Laubach | Democratic | 1855 – 1857 | | |
| Elijah Reed Myer | Republican | 1859 – 1860 | | Pennsylvania State Senator for the 17th district from 1857 to 1858[5] |
| George Landon | Republican | 1859 – 1863 | | |
| William J. Turrell | Republican | 1863 – 1865 | | |
| William M. Randall | Democratic | 1865 – 1873 | | |
| Thomas Valentine Cooper | Republican | 1874 – 1889 | | Pennsylvania State Representative for Delaware County from 1870 to 1871, 1872 to 1873 and 1901 to 1909. Pennsylvania State Senator for the 5th district from 1873 to 1874[6] |
| John Buchanan Robinson | Republican | 1889 – 1892 | | U.S. Representative for Pennsylvania's 6th district from 1891 to 1897[7] |
| Jesse Matlack Baker | Republican | 1893 – 1897 | | Pennsylvania State Representative for Delaware County from 1889-1892[8] |
| William Cameron Sproul | Republican | 1897 – 1919 | | 27th Governor of Pennsylvania from 1919 to 1923[9] |
| Richard J. Baldwin | Republican | 1919 – 1920 | | Speaker of the Pennsylvania House of Representatives from 1917 to 1918[10] |
| Albert Dutton MacDade | Republican | 1921 – 1929 | | |
| John J. McClure | Republican | 1929 – 1937 | | Found guilty and sentenced to 18 months in prison for vice and rum-running, conviction overturned on appeal[11] |
| Weldon Brinton Heyburn | Republican | 1937 – 1949 | | |
| George Watkins | Republican | 1949 – 1960 | | U.S. Representative for Pennsylvania's 7th congressional district from 1965 to 1967. U.S. Representative for Pennsylvania's 9th congressional district from 1967 to 1970[12] |
| Clarence D. Bell | Republican | 1961 – 2002 | | Longest serving state senator in Pennsylvania history[13] |
| Dominic F. Pileggi | Republican | 2002 – 2016 | | Mayor of Chester, Pennsylvania from 1999 to 2002. Republican leader of the Pennsylvania Senate from 2007 to 2014[14] |
| Tom Killion | Republican | 2016 – 2020 | | Pennsylvania State Representative for the 168th district from 2003 to 2016[15] |
| John I. Kane | Democratic | 2020 – present | | |