Paul Marks | |
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| Born | (1926-08-16)August 16, 1926 |
| Died | April 28, 2020(2020-04-28) (aged 93) Manhattan,New York City, NY, U.S. |
| Alma mater | |
| Known for | Paul Marks Prize for Cancer Research |
| Children | Andrew Marks Matthew Marks Elizabeth Ostrer |
| Scientific career | |
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Paul Alan Marks (August 16, 1926 – April 28, 2020) was a medical doctor, researcher and administrator. He was a faculty member and president atMemorial Sloan Kettering Cancer Center.[1][2]
Marks was born inMahanoy City, Pennsylvania, in 1926, to Robert Marks and Sarah Bohorad.[3] Marks attendedColumbia College andColumbia Medical School. After completing postdoctoral research at the United StatesNational Institutes of Health and at theInstitut Pasteur inFrance, he joined the faculty atColumbia University. Marks served as dean of the Medical Faculty at Columbia University from 1970 to 1973.[4] He was president and chief executive officer at Memorial Sloan Kettering from 1980 until 1999.[4] Marks died at his Manhattan home from pulmonary fibrosis and lung cancer on April 28, 2020, at the age of 93.[3]
Marks contributed to the fields ofgenetics andoncology.[4] His recent work was focused onhistone deacetylases (HDACs) and chemicals that interfere with HDAC enzymatic activities (HDAC inhibitors or HDIs). Marks and others found that drugs such asTrichostatin A andSAHA (vorinostat) can serve as anticancer agents.[5]
Marks published more than 400 scientific articles and was the editor-in-chief of journals including theJournal of Clinical Investigation andBlood.[6]
ThePaul Marks Prize for Cancer Research was established by Memorial Sloan Kettering to honor Marks's contributions "as a distinguished scientist and leader".[4] The prize has been awarded every two years since 2001.
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