Until taxonomic revision in 1999,[3]Mannheimia spp. were classified asPasteurella spp., and infections by organisms now calledMannheimia spp., as well as by organisms now calledPasteurella spp., were designated as pasteurellosis. The term "pasteurellosis" is often still applied to mannheimiosis, although such usage has declined.
Sepsis is very rare, but can be as fulminant as septicaemic plague, with high fever,rigors, and vomiting, followed byshock andcoagulopathy.
Pneumonia disease is also rare and appears in patients with some chronicpulmonary pathology. It usually presents as bilateral consolidatingpneumonia, sometimes very severe.
Zoonosis, pasteurellosis can be transmitted to humans through cats.[4]
As the infection is usually transmitted to humans through animal bites, antibiotics usually treat the infection, but medical attention should be sought if the wound is severely swollen. Pasteurellosis is usually treated with high-dosepenicillin if severe. Eithertetracycline orchloramphenicol provides an alternative in beta-lactam-intolerant patients. However, it is most important to treat the wound.[citation needed]
P. multocida causes numerous pathological conditions in domestic animals. It often acts with other infectious agents, such asChlamydia andMycoplasma species andviruses. Environmental conditions (transportation, housing deficiency, and bad weather) also play a role.[citation needed]
These diseases are considered caused byP. multocida, alone or associated with other pathogens:
Shipping fever in cattle and sheep ("shipping fever" may also be caused byMannheimia haemolytica, in the absence ofP. multocida,[5][6] andM. haemolytica serovar A1 is known as the most common cause of the disease.[5] The pathologic condition commonly arises where the causative organism becomes established by secondary infection, following a primary bacterial or viral infection, which may occur after stress, e.g., from handling or transport.[6])
^abBrogden KA, Lehmkuhl HD, Cutlip RC (1998). "Pasteurella haemolytica complicated respiratory infections in sheep and goats".Vet. Res.29 (3–4):233–54.PMID9689740.
^Saigas on the brink: Multidisciplinary analysis of the factors influencing mass mortality events. Richard A. Kock,, Mukhit Orynbayev, Sarah Robinson, Steffen Zuther, Navinder J. Singh, Wendy Beauvais, Eric R. Morgan, Aslan Kerimbayev, Sergei Khomenko, Henny M. Martineau, Rashida Rystaeva, Zamira Omarova, Sara Wolfs, Florent Hawotte, Julien Radoux and Eleanor J. Milner-Gulland. Science Advances 17 Jan 2018: Vol. 4, no. 1, eaao2314 DOI: 10.1126/sciadv.aao2314
