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Paronychia

From Wikipedia, the free encyclopedia
Inflammation of skin surrounding a nail
This article is about the nail disease. For the genus of plants, seeParonychia (plant).
Not to be confused withWhitlow.
Medical condition
Paronychia
Other namesInfection of skin around the nail[1]
SpecialtyDermatology,emergency medicine
TypesAcute and chronic

Paronychia is aninflammation of theskin around the nail, often due to bacteria or fungi.

Its sudden (acute) occurrence is usually due to the bacteriumStaphylococcus aureus. Gradual (chronic) occurrences are typically caused by fungi, commonlyCandida albicans.[2][3][4]

Risk factors for paronychia include frequent hand washing and trauma to the cuticle, such as from chronicnail biting orhangnails.[2]

Treatment typically involves antibiotics for bacterial infections and antifungals for fungal infections. If there is pus formation,incision and drainage may be necessary.[2]

Paronychia is commonly mistakenly used interchangeably withherpetic whitlow orfelon, which are distinct conditions.[2]

Etymology

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The term paronychia is from theGreek:παρωνυχία frompara, "around",onyx, "nail" and the noun suffix-ia.[5][6]

Signs and symptoms

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The index and middle fingers are most commonly affected and may present with redness, swelling and pain. Pus or discharge may be present.[2]

  • An infection of the cuticle secondary to a splinter
    An infection of the cuticle secondary to a splinter
  • Left and right ring fingers of the same person: The distal phalanx of the finger on the right exhibits swelling due to acute paronychia.
    Left and rightring fingers of the same person: Thedistal phalanx of the finger on the right exhibitsswelling due to acute paronychia.
  • Chronic paronychia
    Chronic paronychia

Causes

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Acute paronychia is usually caused by bacteria. It is often treated withantibiotics, either topical (applied to the skin) or oral (taken by mouth), or both. Chronic paronychia is most often caused by ayeast infection of the soft tissues around the nail but can also be traced to abacterial infection. If the infection is continuous, the cause is oftenfungal and needsantifungal cream or paint to be treated.[7]

Risk factors include repeatedly washing hands and trauma to the cuticle such as may occur from repeatednail biting[2] or hangnails. In the context of bartending, it is known as "bar rot".[8]

Painful paronychia in association with a scaly,erythematous, keratotic rash (papules and plaques) of the ears, nose, fingers, and toes may be indicative ofacrokeratosis paraneoplastica, which is associated withsquamous-cellcarcinoma of thelarynx.[9]

Paronychia can occur withdiabetes, drug-inducedimmunosuppression,[10] or systemic diseases such aspemphigus.[11]

Diagnosis

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Types

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Paronychia aka "swollen nail" may be divided as occurring suddenly, acute, or gradually, chronic.[12]

Acute

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Acute paronychia is an infection of the folds of tissue surrounding the nail of a finger or, less commonly, a toe, lasting less than six weeks.[4] The infection generally starts in theparonychium at the side of the nail, with local redness, swelling, and pain.[13]: 660  Acute paronychia is usually caused by direct or indirect trauma to thecuticle or nail fold, and may be from relatively minor events, such as dishwashing, an injury from a splinter or thorn, nail biting, biting or picking at ahangnail, finger sucking, aningrown nail, ormanicure procedures.[14]: 339 

Chronic

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Chronic paronychia is an infection of the folds of tissue surrounding the nail of a finger or, less commonly, a toe, lasting more than six weeks.[4] It is anail disease prevalent in individuals whose hands or feet are subject to moist local environments, and is often due tocontact dermatitis.[13]: 660  In chronic paronychia, the cuticle separates from the nail plate, leaving the region between the proximal nail fold and thenail plate vulnerable to infection.[15]: 343  It can be the result of dish washing, finger sucking, aggressively trimming thecuticles, or frequent contact with chemicals (mildalkalis,acids, etc.).

Alternatively, paronychia may be divided as follows:[13]

  • Candidal paronychia is an inflammation of the nail fold produced byC. albicans.[12]: 310 
  • Pyogenic paronychia is an inflammation of the folds of skin surrounding the nail caused by bacteria.[12]: 254  Generally, acute paronychia ispyogenic, as it is usually caused by a bacterial infection.[4]

Differential

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Differential diagnosis of paronychia includes:

  • Cellulitis is a superficial infection and presents as erythema and swelling to the affected portion of the body with no area of fluctuance. Treatment is with oral antibiotics.[16]
  • Whitlow or felon is a subcutaneous infection of the digital pulp space. The area becomes warm, red, tense, and very painful due to the confinement of the infection, creating pressure in the individual compartments created by the septa of the finger pad. These require excision and drainage, usually with a longitudinal incision and blunt dissection to ensure adequate drainage.[2][16]
  • Herpetic whitlow is a viral infection of the distal finger caused by HSV. Patients usually develop a burning, pruritic sensation before the infection erupts. A physical exam shows vesicles and vesicopustules, along with pain and erythema. It is important to not confuse this with a felon or a paronychia as incision and drainage of herpetic whitlow could result in a secondary bacterial infection and failure to heal.[16]
  • Onychomycosis is a fungal infection of the nail that causes whitish-yellowish discoloration. Sometimes, it is difficult to treat and requires oral antibiotics instead of topical.[16]
  • Nail psoriasis can affect the fingernails and toenails. It may cause thickening of the nails with areas of pitting, ridges, irregular contour, and even raising of the nail from the nail bed.[16]
  • Squamous-cell carcinoma is mainly cancer of the skin, but can also affect the nail bed. It is a rare malignant subungual tumor subject to misdiagnosis as chronic paronychia.[16]

Treatment

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Incision after paronychia of the thumb, partial removal of the nail

When no pus is present, warm soaks for acute paronychia are reasonable, though evidence to support its use is lacking.[17]

Chronic paronychia is treated by avoiding whatever is causing it, atopical antifungal, and atopical steroid. In those who do not improve following these measures, oral antifungals and steroids may be used or the nail fold may be removed surgically.[18]

Antibiotics

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No strong evidence has been found to recommend topical vs. oral antibiotics, and this may be physician-dependent based on experience. Antibiotics used should haveS. aureus coverage. Topical antibiotics used may be atriple antibiotic ointment, bacitracin, or mupirocin. In patients failing topical treatment or more severe cases, oral antibiotics are an option; dicloxacillin or cephalexin can be used. Indications for antibiotics with anaerobic coverage include patients where a concern exists for oral inoculation; this would require the addition of clindamycin or amoxicillin-clavulanate.[16]Antibiotics such asclindamycin orcephalexin are also often used, the first being more effective in areas whereMRSA is common.[17] If signs of anabscess (the presence of pus) are seen, drainage is recommended.[17]

Epidemiology

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Paronychia is more common in women than in men, by a ratio of three to one. Usually, they affect manual-labor workers or people in occupations that require them to have their hands or feet submerged in water for prolonged periods (e.g., dishwashers). Middle-aged females are at the highest risk of infection.[16]

References

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  1. ^"Paronychia: MedlinePlus Medical Encyclopedia".medlineplus.gov. Retrieved26 April 2019.
  2. ^abcdefgJames G. Marks; Jeffrey J. Miller (2013)."21. Nail disorders".Lookingbill and Marks' Principles of Dermatology E-Book (Fifth ed.). Elsevier Saunders. p. 256.ISBN 978-1-4557-2875-6.
  3. ^Rigopoulos D, Larios G, Gregoriou S, Alevizos A (February 2008). "Acute and chronic paronychia".Am Fam Physician.77 (3):339–46.PMID 18297959.
  4. ^abcdRockwell PG (March 2001). "Acute and chronic paronychia".Am Fam Physician.63 (6):1113–6.PMID 11277548.
  5. ^Harper, Douglas."paronychia".Online Etymology Dictionary.
  6. ^παρωνυχία,παρά,ὄνυξ.Liddell, Henry George;Scott, Robert;A Greek–English Lexicon at thePerseus Project.
  7. ^"Doctor's advice Q: Whitlow (paronychia)".bbc.co.uk. Archived fromthe original on August 30, 2006. Retrieved2008-05-10.
  8. ^"Bar Rot".The Truth About Bartending. January 27, 2012. Archived fromthe original on 2013-03-22.
  9. ^Karen Allen, MD (2005-08-17)."eMedicine – Acrokeratosis Neoplastica".Medscape.
  10. ^Paronychia~clinical ateMedicine
  11. ^Serratos BD, Rashid RM (2009)."Nail disease in pemphigus vulgaris".Dermatol. Online J.15 (7): 2.doi:10.5070/D34X05D6VH.PMID 19903430.
  12. ^abcJames, William D.; Berger, Timothy G. (2006).Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier.ISBN 978-0-7216-2921-6.
  13. ^abcFreedberg, Irwin M., ed. (2003).Fitzpatrick's Dermatology in General Medicine (6th ed.). McGraw-Hill Publishing Company.ISBN 978-0071380768.
  14. ^Rigopoulos, Dimitris; Larios, George; Gregoriou, Stamatis; Alevizos, Alevizos (2008)."Acute and Chronic Paronychia"(PDF).American Family Physician.77 (3):339–346.PMID 18297959. RetrievedJanuary 7, 2013.
  15. ^Rigopoulos, Dimitris; Larios, George; Gregoriou, Stamatis; Alevizos, Alevizos (2008)."Acute and Chronic Paronychia"(PDF).American Family Physician.77 (3):339–346.PMID 18297959. RetrievedJanuary 8, 2013.
  16. ^abcdefghDulski, Anne; Edwards, Christopher W (2020). "Paronychia".Statpearls.PMID 31335027. Text was copied from this source, which is available under aCreative Commons Attribution 4.0 International License.
  17. ^abcRitting, AW; O'Malley, MP; Rodner, CM (May 2012). "Acute paronychia".The Journal of Hand Surgery.37 (5):1068–70, quiz page 1070.doi:10.1016/j.jhsa.2011.11.021.PMID 22305431.S2CID 29619616.
  18. ^Rigopoulos, Dimitris; Larios, George; Gregoriou, Stamatis; Alevizos, Alevizos (1 February 2008)."Acute and Chronic Paronychia".American Family Physician.77 (3):339–346.ISSN 0002-838X.PMID 18297959.

External links

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Wikimedia Commons has media related toParonychia (disease).
Classification
External resources
Diseases of the skin and appendages by morphology
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Epidermal
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