Sorrentino was born to a bank director and a housewife in theArenella district ofNaples and grew up in theVomero district. He has a brother, Marco, and a sister, Daniela. He became an orphan at 16 after losing his parents to an accidentalcarbon monoxide leak in theirRoccaraso mountain holiday house.[4] He studied economics at theUniversity of Naples Federico II but did not graduate. He is married to his childhood friend Daniela D'Antonio, a journalist. They have two children.
His first film as a screenwriter,The Dust of Naples, was released in 1998. He also began directing short movies, includingL'amore non ha confini in 1998 andLa notte lunga in 2001. His feature-length debut wasOne Man Up, for which he was awarded theNastro D'Argento prize.
He achieved international recognition in 2004 for his thrillerThe Consequences of Love. The film, which explores the mindset of a lonely businessman being used as a pawn by theMafia, won many awards and was nominated for thePalme d'Or at the2004 Cannes Film Festival.[5] Sorrentino's next feature,The Family Friend, was shown at theCannes Film Festival in May[6] and theLondon Film Festival in October 2006; it tells the story of a malicious septuagenarianloan shark who develops a fixation with the daughter of one of his customers. Sorrentino made his acting debut the same year with a cameo appearance inNanni Moretti's filmThe Caiman, which was also shown at the 2006 London Film Festival.
Sorrentino's following film,Il Divo (2008), is a dramatised biopic ofGiulio Andreotti, a controversial Italian politician. The feature, which won thePrix du Jury at Cannes Film Festival, sees Sorrentino reunited withThe Consequences of Love starToni Servillo, who plays the part of Andreotti. In 2009, it was announced Sorrentino wrote the screenplay for a film version ofNiccolò Ammaniti's novelTi prendo e ti porto via (Steal You Away).[7]This Must Be the Place (2011) marked the English-language feature debut of the Italian filmmaker. The plot centres on a middle-aged, wealthy rock star, played by two-time Academy Award winnerSean Penn, who becomes bored in his retirement and takes on the quest of finding the guard of the German camp where his father was imprisoned, who now lives in hiding in the United States. The film was co-written by Sorrentino and Umberto Contarello,[8] and premiered in competition at the2011 Cannes Film Festival.[9]
In 2019, it was announced that Sorrentino would be directingJennifer Lawrence as mob informant Arlyne Brickman inMob Girl. The film is an adaptation of thebook of the same name byTeresa Carpenter.[17] Sorrentino will also be working as a co-producer on the film with Lawrence, as well as co-writing the screenplay.[17][18]
Sorrentino’s 2021 feature,The Hand of God, filmed in Naples, contains autobiographical elements. In an article about the film,The Guardian called it a coming of age story that was Sorrentino's "most personal" film to date, representing a departure from the detached style of some of his earlier work. Sorrentino also called the film "a completely different movie" in terms of style and, regarding the autobiographical elements, acknowledged that "almost everything is true."[19] The film, which reunited Sorrentino with Toni Servillo, was selected as the Italian entry for theAcademy Award for Best International Feature Film at the94th Academy Awards.[20] The film was nominated but ultimately lost to theRyusuke Hamaguchi filmDrive My Car (2021).
As announced in 2021, Sorrentino will next direct the biopicSue[21] starring and produced by Lawrence as well. The movie — to be written by Lauren Schuker Blum, Rebecca Angelo andJohn Logan — will chronicle the life of Hollywood agentSue Mengers asApple Studios backs the film.[22] In a fierce bidding war for the film between Apple andNetflix, the package offers ranged from $80 million to $95 million for the budget.[23] In 2023 it was reported Sorrentino was directing another "love letter to Naples",Parthenope, the cast to includeGary Oldman.[24]
In 2025, Sorrentino confirmed toEntertainment Weekly that the Jennifer Lawrence projectsMob Girl andSue would not be going forward.[25] In August 2025, he will be honoured with theHonorary Heart of Sarajevo Award for "outstanding contribution to the art of cinema". A retrospective of his films will also be featured as part of the31st Sarajevo Film Festival’s "Tribute To" program.[26]