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Pamicogrel

From Wikipedia, the free encyclopedia
Pamicogrel
Names
Preferred IUPAC name
Ethyl {2-[4,5-bis(4-methoxyphenyl)-1,3-thiazol-2-yl]-1H-pyrrol-1-yl}acetate
Other names
KB 3022, Paminate
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C25H24N2O4S/c1-4-31-22(28)16-27-15-5-6-21(27)25-26-23(17-7-11-19(29-2)12-8-17)24(32-25)18-9-13-20(30-3)14-10-18/h5-15H,4,16H2,1-3H3
    Key: ISCHOARKJADAKJ-UHFFFAOYSA-N
  • InChI=1/C25H24N2O4S/c1-4-31-22(28)16-27-15-5-6-21(27)25-26-23(17-7-11-19(29-2)12-8-17)24(32-25)18-9-13-20(30-3)14-10-18/h5-15H,4,16H2,1-3H3
    Key: ISCHOARKJADAKJ-UHFFFAOYAC
  • CCOC(=O)CN1C=CC=C1C2=NC(=C(S2)C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC
Properties
C25H24N2O4S
Molar mass448.54 g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
Chemical compound

Pamicogrel is acyclooxygenase inhibitor that was underdevelopment for itsanti-platelet-aggregation effects.[1][2]

References

[edit]
  1. ^Light P (September 1999). "Pamicogrel (Kanebo)".IDrugs.2 (9):938–42.PMID 16121308.
  2. ^"Pamicogrel inhibits platelet aggregation".Inpharma Weekly.1272 (1): 11. January 2001.doi:10.2165/00128413-200112720-00021.S2CID 195132149.

External links

[edit]


Receptor
(ligands)
DP (D2)Tooltip Prostaglandin D2 receptor
DP1Tooltip Prostaglandin D2 receptor 1
DP2Tooltip Prostaglandin D2 receptor 2
EP (E2)Tooltip Prostaglandin E2 receptor
EP1Tooltip Prostaglandin EP1 receptor
EP2Tooltip Prostaglandin EP2 receptor
EP3Tooltip Prostaglandin EP3 receptor
EP4Tooltip Prostaglandin EP4 receptor
Unsorted
FP (F)Tooltip Prostaglandin F receptor
IP (I2)Tooltip Prostacyclin receptor
TP (TXA2)Tooltip Thromboxane receptor
Unsorted
Enzyme
(inhibitors)
COX
(
PTGS)
PGD2STooltip Prostaglandin D synthase
PGESTooltip Prostaglandin E synthase
PGFSTooltip Prostaglandin F synthase
PGI2STooltip Prostacyclin synthase
TXASTooltip Thromboxane A synthase
Others


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