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PTGFRN

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
PTGFRN
Identifiers
AliasesPTGFRN, CD315, CD9P-1, EWI-F, FPRP, SMAP-6, prostaglandin F2 receptor inhibitor
External IDsOMIM:601204;MGI:1277114;HomoloGene:7908;GeneCards:PTGFRN;OMA:PTGFRN - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for PTGFRN
Genomic location for PTGFRN
Band1p13.1Start116,909,916bp[1]
End116,990,353bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for PTGFRN
Genomic location for PTGFRN
Band3|3 F2.2Start100,947,548bp[2]
End101,017,594bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • cardiac muscle tissue of right atrium

  • ventricular zone

  • muscle layer of sigmoid colon

  • myocardium of left ventricle

  • right auricle of heart

  • left uterine tube

  • body of uterus

  • olfactory zone of nasal mucosa

  • myometrium

  • right ventricle
Top expressed in
  • umbilical cord

  • atrium

  • ventricular zone

  • left lung lobe

  • right lung lobe

  • Gonadal ridge

  • atrioventricular valve

  • molar

  • urinary bladder

  • endocardial cushion
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

5738

19221

Ensembl

ENSG00000134247

ENSMUSG00000027864

UniProt

Q9P2B2

Q9WV91

RefSeq (mRNA)

NM_020440

NM_011197

RefSeq (protein)

NP_065173

NP_035327

Location (UCSC)Chr 1: 116.91 – 116.99 MbChr 3: 100.95 – 101.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Prostaglandin F2 receptor negative regulator is aprotein that in humans is encoded by thePTGFRNgene.[5][6] PTGFRN has also been designated asCD315 (cluster of differentiation 315).


Interactions

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PTGFRN has been shown tointeract withCD9[7][8] andCD81.[7][8]

References

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  1. ^abcGRCh38: Ensembl release 89: ENSG00000134247 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000027864 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Orlicky DJ, Berry R, Sikela JM (Jul 1996). "Human chromosome 1 localization of the gene for a prostaglandin F2alpha receptor negative regulatory protein".Hum Genet.97 (5):655–8.doi:10.1007/BF02281878.PMID 8655148.S2CID 21645802.
  6. ^"Entrez Gene: PTGFRN prostaglandin F2 receptor negative regulator".
  7. ^abCharrin, S; Le Naour F; Oualid M; Billard M; Faure G; Hanash S M; Boucheix C; Rubinstein E (Apr 2001)."The major CD9 and CD81 molecular partner. Identification and characterization of the complexes".J. Biol. Chem.276 (17). United States:14329–37.doi:10.1074/jbc.M011297200.ISSN 0021-9258.PMID 11278880.
  8. ^abStipp, C S; Orlicky D; Hemler M E (Feb 2001)."FPRP, a major, highly stoichiometric, highly specific CD81- and CD9-associated protein".J. Biol. Chem.276 (7). United States:4853–62.doi:10.1074/jbc.M009859200.ISSN 0021-9258.PMID 11087758.

Further reading

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External links

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