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PSKH1

From Wikipedia, the free encyclopedia
Enzyme found in humans

PSKH1
Identifiers
AliasesPSKH1, protein serine kinase H1
External IDsOMIM:177015;MGI:3528383;HomoloGene:48461;GeneCards:PSKH1;OMA:PSKH1 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for PSKH1
Genomic location for PSKH1
Band16q22.1Start67,893,254bp[1]
End67,929,676bp[1]
Gene location (Mouse)
Chromosome 8 (mouse)
Chr.Chromosome 8 (mouse)[2]
Chromosome 8 (mouse)
Genomic location for PSKH1
Genomic location for PSKH1
Band8|8 D3Start106,627,073bp[2]
End106,658,410bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • stromal cell of endometrium

  • mucosa of transverse colon

  • apex of heart

  • body of stomach

  • body of pancreas

  • right coronary artery

  • popliteal artery

  • tibial arteries

  • left ovary

  • left adrenal cortex
Top expressed in
  • hand

  • genital tubercle

  • zygote

  • internal carotid artery

  • tail of embryo

  • external carotid artery

  • secondary oocyte

  • foot

  • maxillary prominence

  • mandibular prominence
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

5681

244631

Ensembl

ENSG00000159792

ENSMUSG00000048310

UniProt

P11801

Q91YA2

RefSeq (mRNA)

NM_006742

NM_173432

RefSeq (protein)

NP_006733

NP_775608

Location (UCSC)Chr 16: 67.89 – 67.93 MbChr 8: 106.63 – 106.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Serine/threonine-protein kinase H1 is anenzyme that in humans is encoded by thePSKH1gene.[5][6]

Interactions

[edit]

PSKH1 has been shown tointeract withCDC6.[7]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000159792 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000048310 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Larsen F, Solheim J, Kristensen T, Kolstø AB, Prydz H (February 1994). "A tight cluster of five unrelated human genes on chromosome 16q22.1".Hum Mol Genet.2 (10):1589–95.doi:10.1093/hmg/2.10.1589.PMID 8268911.
  6. ^"Entrez Gene: PSKH1 protein serine kinase H1".
  7. ^Petersen BO, Lukas J, Sørensen CS, Bartek J, Helin K (January 1999)."Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization".EMBO J.18 (2):396–410.doi:10.1093/emboj/18.2.396.PMC 1171134.PMID 9889196.

Further reading

[edit]
Non-specific serine/threonine protein kinases (EC 2.7.11.1)
Pyruvate dehydrogenase kinase (EC 2.7.11.2)
Dephospho-(reductase kinase) kinase (EC 2.7.11.3)
3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase (EC 2.7.11.4)
(isocitrate dehydrogenase (NADP+)) kinase (EC 2.7.11.5)
(tyrosine 3-monooxygenase) kinase (EC 2.7.11.6)
Myosin-heavy-chain kinase (EC 2.7.11.7)
Fas-activated serine/threonine kinase (EC 2.7.11.8)
Goodpasture-antigen-binding protein kinase (EC 2.7.11.9)
  • -
IκB kinase (EC 2.7.11.10)
cAMP-dependent protein kinase (EC 2.7.11.11)
cGMP-dependent protein kinase (EC 2.7.11.12)
Protein kinase C (EC 2.7.11.13)
Rhodopsin kinase (EC 2.7.11.14)
Beta adrenergic receptor kinase (EC 2.7.11.15)
G-protein coupled receptor kinases (EC 2.7.11.16)
Ca2+/calmodulin-dependent (EC 2.7.11.17)
Myosin light-chain kinase (EC 2.7.11.18)
Phosphorylase kinase (EC 2.7.11.19)
Elongation factor 2 kinase (EC 2.7.11.20)
Polo kinase (EC 2.7.11.21)
Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30)
Polo kinase (EC 2.7.11.21)
Cyclin-dependent kinase (EC 2.7.11.22)
(RNA-polymerase)-subunit kinase (EC 2.7.11.23)
Mitogen-activated protein kinase (EC 2.7.11.24)
MAP3K (EC 2.7.11.25)
Tau-protein kinase (EC 2.7.11.26)
(acetyl-CoA carboxylase) kinase (EC 2.7.11.27)
  • -
Tropomyosin kinase (EC 2.7.11.28)
  • -
Low-density-lipoprotein receptor kinase (EC 2.7.11.29)
  • -
Receptor protein serine/threonine kinase (EC 2.7.11.30)
MAP2K
Activity
Regulation
Classification
Kinetics
Types
Portal:


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