Movatterモバイル変換

[0]ホーム
URL:

Jump to content
WikipediaThe Free Encyclopedia
Search

PSCDBP

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
CYTIP
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

2Z17

Identifiers
AliasesCYTIP, B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP, cytohesin 1 interacting protein
External IDsOMIM:604448;MGI:2183535;HomoloGene:3167;GeneCards:CYTIP;OMA:CYTIP - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for CYTIP
Genomic location for CYTIP
Band2q24.1Start157,414,619bp[1]
End157,488,961bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for CYTIP
Genomic location for CYTIP
Band2|2 C1.1Start58,019,149bp[2]
End58,085,544bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • blood

  • bone marrow cells

  • white blood cell

  • monocyte

  • appendix

  • lymph node

  • granulocyte

  • epithelium of colon

  • epithelium of nasopharynx

  • spleen
Top expressed in
  • granulocyte

  • spleen

  • mesenteric lymph nodes

  • right lung lobe

  • thymus

  • blood

  • tibiofemoral joint

  • lactiferous gland

  • bone marrow

  • Paneth cell
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9595

227929

Ensembl

ENSG00000115165

ENSMUSG00000026832

UniProt

O60759

Q91VY6

RefSeq (mRNA)

NM_004288

NM_139200

RefSeq (protein)

NP_004279

NP_631939

Location (UCSC)Chr 2: 157.41 – 157.49 MbChr 2: 58.02 – 58.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cytohesin-interacting protein is aprotein that in humans is encoded by theCYTIPgene.[5][6][7][8]

The protein encoded by this gene contains 2leucine zipper domains and a putative C-terminal nuclear targeting signal, and it does not have anyhydrophobic regions. This protein is expressed weakly in resting NK and T cells.[8]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000115165 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000026832 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Dixon B, Sahely B, Liu L, Pohajdak B (Jan 1994). "Cloning a cDNA from human NK/T cells which codes for an unusual leucine zipper containing protein".Biochim Biophys Acta.1216 (2):321–4.doi:10.1016/0167-4781(93)90165-a.PMID 8241278.
  6. ^Kim HS (Jun 1999). "Assignment of the human B3-1 gene (PSCDBP) to chromosome 2 band q11.2 by radiation hybrid mapping".Cytogenet Cell Genet.84 (1–2): 95.doi:10.1159/000015226.PMID 10343115.S2CID 7420858.
  7. ^Tang P, Cheng TP, Agnello D, Wu CY, Hissong BD, Watford WT, Ahn HJ, Galon J, Moss J, Vaughan M, O'Shea JJ, Gadina M (Mar 2002)."Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity".Proc Natl Acad Sci USA.99 (5):2625–9.Bibcode:2002PNAS...99.2625T.doi:10.1073/pnas.052712999.PMC 122398.PMID 11867758.
  8. ^ab"Entrez Gene: PSCDBP pleckstrin homology, Sec7 and coiled-coil domains, binding protein".

Further reading

[edit]


Stub icon

This article on agene on humanchromosome 2 is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=PSCDBP&oldid=1142690501"
Categories:
Hidden categories:
[8]ページ先頭
©2009-2025 Movatter.jp