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P2RY13

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
P2RY13
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

2B6U

Identifiers
AliasesP2RY13, GPCR1, GPR86, GPR94, P2Y13, SP174, FKSG77, purinergic receptor P2Y13
External IDsOMIM:606380;MGI:1921441;HomoloGene:12543;GeneCards:P2RY13;OMA:P2RY13 - orthologs
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for P2RY13
Genomic location for P2RY13
Band3q25.1Start151,326,312bp[1]
End151,329,549bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for P2RY13
Genomic location for P2RY13
Band3|3 DStart59,115,313bp[2]
End59,118,303bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • monocyte

  • blood

  • granulocyte

  • spleen

  • bone marrow

  • trabecular bone

  • bone marrow cells

  • appendix

  • lymph node

  • testicle
Top expressed in
  • granulocyte

  • mesenteric lymph nodes

  • spleen

  • lumbar subsegment of spinal cord

  • Region I of hippocampus proper

  • dentate gyrus of hippocampal formation granule cell

  • embryo

  • bone marrow

  • visual cortex

  • stroma of bone marrow
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

53829

74191

Ensembl

ENSG00000181631

ENSMUSG00000036362

UniProt

Q9BPV8

Q9D8I2

RefSeq (mRNA)

NM_023914
NM_176894

NM_028808

RefSeq (protein)

NP_795713

NP_083084

Location (UCSC)Chr 3: 151.33 – 151.33 MbChr 3: 59.12 – 59.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

P2Y purinoceptor 13 is aprotein that in humans is encoded by theP2RY13gene.[5][6][7]

The product of this gene, P2Y13, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. Two transcript variants encoding the same protein have been identified for this gene.[7]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000181631Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000036362Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Wittenberger T, Schaller HC, Hellebrand S (Mar 2001). "An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors".J Mol Biol.307 (3):799–813.doi:10.1006/jmbi.2001.4520.PMID 11273702.
  6. ^Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes".Gene.275 (1):83–91.doi:10.1016/S0378-1119(01)00651-5.PMID 11574155.
  7. ^ab"Entrez Gene: P2RY13 purinergic receptor P2Y, G-protein coupled, 13".

Further reading

[edit]

External links

[edit]
  • "P2Y Receptors: P2Y13".IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived fromthe original on 2016-03-03. Retrieved2008-12-09.

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

Neurotransmitter
Adrenergic
Purinergic
Serotonin
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signaling molecules
Eicosanoid
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Taste, bitter
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(ligands)
P0 (adenine)
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(adenosine)
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(nucleotide)
P2X
(ATPTooltip Adenosine triphosphate)
P2Y
Transporter
(blockers)
CNTsTooltip Concentrative nucleoside transporters
ENTsTooltip Equilibrative nucleoside transporters
PMATTooltip Plasma membrane monoamine transporter
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