P2Y purinoceptor 11 is aprotein that in humans is encoded by theP2RY11gene.[3][4]
The product of this gene, P2Y11, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occurring read-through transcripts, resulting fromintergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.[4]
This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.
 | Thistransmembrane receptor-related article is astub. You can help Wikipedia byexpanding it. |
