| Combination of | |
|---|---|
| Oxycodone | Opioid analgesic |
| Acetaminophen | Anilide analgesic |
| Clinical data | |
| Trade names | Percocet, others |
| AHFS/Drugs.com | |
| License data | |
| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| ChemSpider |
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| KEGG | |
| CompTox Dashboard(EPA) | |
 N Y (what is this?) (verify) | |
Oxycodone/paracetamol, sold under the brand namePercocet among others,[2] is afixed-dose combination of the opioidoxycodone withparacetamol (acetaminophen), used to treat moderate to severepain.[1]
In 2023, it was the 93rd most commonly prescribed medication in the United States, with more than 7 million prescriptions.[3][4]
The United StatesFood and Drug Administration (FDA) first approved oxycodone/paracetamol in 1976, under application ANDA 085106.[5]
Percocet is often calledperc for short.[6][7] Since the early 2010s, the medication has commonly been name-dropped in songs from multiple genres, such asFuture's 2017 song "Mask Off".[6]
In June 2009, an FDA advisory panel recommended that Percocet,Vicodin, and every other combination of acetaminophen withnarcoticanalgesics[8] be limited in their sales because of their contributions to an alleged 400 acetaminophen-related deaths in the U.S. each year, that were attributed toacetaminophen overdose and associated liver damage.[9]
In December 2009, a study found a fivefold increase in oxycodone-related deaths inOntario, Canada (mostly accidental) between 1991 and 2007; this led to a doubling of all opioid-related deaths in Ontario over the same period.[10][11][12]
Also known as: Percs, blue dynamite. [...] Percocet has become a favorite reference in rap music [...] The rapper Future elevated Perc-worship to a new status in the chorus of his hit 'Mask Off'
Street Title: Hillbilly Heroin, Kicker, OC, Ox, Roxy, Perc, Oxy
| pyrazolones / pyrazolidines | |
|---|---|
| salicylates | |
| acetic acid derivatives and related substances | |
| oxicams | |
| propionic acid derivatives (profens) |
|
| n-arylanthranilic acids (fenamates) | |
| COX-2 inhibitors (coxibs) | |
| other | |
| NSAID combinations | |
Key:underline indicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;†withdrawn drugs;‡veterinary use. | |
