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Oxametacin

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Oxametacin
Clinical data
ATC code
Identifiers
  • 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-hydroxyacetamide
CAS Number
PubChemCID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.043.785Edit this at Wikidata
Chemical and physical data
FormulaC19H17ClN2O4
Molar mass372.81 g·mol−1
3D model (JSmol)
  • CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)NO
  • InChI=1S/C19H17ClN2O4/c1-11-15(10-18(23)21-25)16-9-14(26-2)7-8-17(16)22(11)19(24)12-3-5-13(20)6-4-12/h3-9,25H,10H2,1-2H3,(H,21,23) ☒N
  • Key:AJRNYCDWNITGHF-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Oxametacin (oroxamethacin) is anon-steroidal anti-inflammatory drug.[1]

Hydrolysis of the amide group is one of the synthetic pathways toDeboxamet (ChemDrug).

References

[edit]
  1. ^Schweiger J (1999)."Oxametacin". In von Bruchhausen F, Ebel S, Hackenthal E, Holzgrabe U (eds.).Hagers Handbuch der Pharmazeutischen Praxis: Stoffe L-Z Folgeband 5 (in German) (5th, vollständig neubearbeitete Auflage ed.). Berlin, Heidelberg. pp. 367–368.ISBN 978-3-642-58388-9.{{cite book}}: CS1 maint: location missing publisher (link)
pyrazolones /
pyrazolidines
salicylates
acetic acid derivatives
and related substances
oxicams
propionic acid
derivatives (profens)
n-arylanthranilic
acids (fenamates)
COX-2 inhibitors
(coxibs)
other
NSAID
combinations
Key:underline indicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;withdrawn drugs;veterinary use.
Receptor
(ligands)
DP (D2)Tooltip Prostaglandin D2 receptor
DP1Tooltip Prostaglandin D2 receptor 1
DP2Tooltip Prostaglandin D2 receptor 2
EP (E2)Tooltip Prostaglandin E2 receptor
EP1Tooltip Prostaglandin EP1 receptor
EP2Tooltip Prostaglandin EP2 receptor
EP3Tooltip Prostaglandin EP3 receptor
EP4Tooltip Prostaglandin EP4 receptor
Unsorted
FP (F)Tooltip Prostaglandin F receptor
IP (I2)Tooltip Prostacyclin receptor
TP (TXA2)Tooltip Thromboxane receptor
Unsorted
Enzyme
(inhibitors)
COX
(
PTGS)
PGD2STooltip Prostaglandin D synthase
PGESTooltip Prostaglandin E synthase
PGFSTooltip Prostaglandin F synthase
PGI2STooltip Prostacyclin synthase
TXASTooltip Thromboxane A synthase
Others


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