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Ornithine translocase

From Wikipedia, the free encyclopedia
Family of transport proteins
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
Identifiers
SymbolSLC25A15
Alt. symbolsORNT1, HHH
NCBI gene10166
HGNC10985
OMIM603861
RefSeqNM_014252
UniProtQ9Y619
Other data
LocusChr. 13q14
Search for
StructuresSwiss-model
DomainsInterPro

Ornithine translocase is responsible for transportingornithine from thecytosol into themitochondria in theurea cycle. It is highly expressed in the liver and pancreas.

Pathology

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A disorder is associated withornithine translocase deficiency, and a form ofhyperammonemia.

See also

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External links

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By group
SLC1–10
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SLC11–20
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SLC21–30
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SLC31–40
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SLC41–48
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SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)
Main cycle
mitochondrial matrix:
cytosol:
Regulatory/transport


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