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Olopatadine/mometasone

From Wikipedia, the free encyclopedia
Combination drug

Pharmaceutical compound
Olopatadine/mometasone
Clinical data
Trade namesRyaltris
Other namesGSP 301
AHFS/Drugs.comRyaltris
License data
Pregnancy
category
Routes of
administration
Nasal spray
ATC code
Legal status
Legal status
Identifiers
KEGG

Olopatadine/mometasone, sold under the brand nameRyaltris, is afixed-dose combination medication for the treatment ofallergic rhinitis andrhinoconjunctivitis in adults and adolescents twelve years of age and older.[1][4][5] It containsolopatadine hydrochloride andmometasone furoate monohydrate.[1][4] It issprayed into the nose.[1][4]

Common side effects include an unpleasant taste (dysgeusia).[1]

It was approved for medical use in Australia in December 2019,[1][6] and in the United States in January 2022.[4]

References

[edit]
  1. ^abcdefg"Ryaltris (olopatadine hydrochloride and mometasone furoate monohydrate) Nasal Spray". Retrieved25 July 2020.
  2. ^"Ryaltris Product information".Health Canada. 17 March 2023. Retrieved16 February 2025.
  3. ^"Details for: Ryaltris".Drug and Health Products Portal. 17 March 2023. Retrieved16 February 2025.
  4. ^abcde"Ryaltris- olopatadine hydrochloride and mometasone furoate spray, metered".DailyMed. 9 January 2022. Retrieved20 June 2022.
  5. ^Chen R, Zheng D, Zhang Y, Sima G (September 2021). "Efficacy and safety of twice-daily olopatadine-mometasone combination nasal spray (GSP301) in the treatment of allergic rhinitis: a systematic review and meta-analysis".European Archives of Oto-rhino-laryngology.279 (4):1691–1699.doi:10.1007/s00405-021-07085-w.PMID 34591150.S2CID 238223252.
  6. ^"Ryaltris nasal spray approved in Australia".OINDPnews. 20 December 2019. Retrieved25 July 2020.

External links

[edit]
  • Clinical trial numberNCT02631551 for "Efficacy and Safety of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Seasonal Allergic Rhinitis (SAR) (GSP 301-301)" atClinicalTrials.gov
  • Clinical trial numberNCT02870205 for "Efficacy and Safety of GSP 301 Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (SAR) (GSP 301-304)" atClinicalTrials.gov
Decongestants and other nasal preparations (R01)
Topical
Sympathomimetics, plain
Antiallergic agents,
excluding corticosteroids
Corticosteroids
Other nasal preparations
Combination products
Systemic use:
Sympathomimetics
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