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| Names | |
|---|---|
| IUPAC name 2-[Methyl-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amino]acetic acid | |
| Identifiers | |
3D model (JSmol) | |
| ChEMBL | |
| ChemSpider | |
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| Properties | |
| C19H20F3NO3 | |
| Molar mass | 367.368 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
ORG-24598 is a selective inhibitor of thetype 1 glycine transporter.[1]
A test in rats has showed that combiningvarenicline,bupropion, and an indirect glycine agonist (such as ORG-24598) could be beneficial for treatment ofalcohol use disorder.[2]
Studies have shown that glycine re-uptake inhibitors selective for the type 1 transporter may be useful for the treatment of certain schizophrenia symptoms.[3][4]
