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OR5D18

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR5D18
Identifiers
AliasesOR5D18, OR11-143, olfactory receptor family 5 subfamily D member 18
External IDsMGI:3030989;HomoloGene:133739;GeneCards:OR5D18;OMA:OR5D18 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR5D18
Genomic location for OR5D18
Band11q12.1Start55,819,630bp[1]
End55,820,571bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for OR5D18
Genomic location for OR5D18
Band2|2 DStart87,771,989bp[2]
End87,775,481bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • gonad
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

219438

258636

Ensembl

ENSG00000186119

ENSMUSG00000075145

UniProt

Q8NGL1

Q8VFR3

RefSeq (mRNA)

NM_001001952

NM_146643

RefSeq (protein)

NP_001001952

NP_666854

Location (UCSC)Chr 11: 55.82 – 55.82 MbChr 2: 87.77 – 87.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 5D18 is aprotein that in humans is encoded by theOR5D18gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000186119Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000075145Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: OR5D18 olfactory receptor, family 5, subfamily D, member 18".

Further reading

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External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


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