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OR2AE1

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens

OR2AE1
Identifiers
AliasesOR2AE1, OR2AE2, olfactory receptor family 2 subfamily AE member 1
External IDsHomoloGene:128272;GeneCards:OR2AE1;OMA:OR2AE1 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for OR2AE1
Genomic location for OR2AE1
Band7q22.1Start99,876,062bp[1]
End99,877,033bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right coronary artery

  • skeletal muscle tissue

  • duodenum

  • gastric mucosa

  • muscle of leg

  • triceps surae

  • gastrocnemius muscle

  • islet of Langerhans

  • prefrontal cortex

  • anterior pituitary
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

81392

n/a

Ensembl

ENSG00000244623

n/a

UniProt

Q8NHA4

n/a

RefSeq (mRNA)

NM_001005276

n/a

RefSeq (protein)

NP_001005276

n/a

Location (UCSC)Chr 7: 99.88 – 99.88 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 2AE1 is aprotein that in humans is encoded by theOR2AE1gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

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References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000244623Ensembl, May 2017
  2. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ab"Entrez Gene: OR2AE1 olfactory receptor, family 2, subfamily AE, member 1".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

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