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| Names | |
|---|---|
| IUPAC name 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indole | |
| Other names N-Desmethylibogaminalog | |
| Identifiers | |
3D model (JSmol) | |
| ChEMBL | |
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| Properties | |
| C12H14N2 | |
| Molar mass | 186.258 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Noribogaminalog, orN-desmethylibogaminalog, also known as1,2,3,4,5,6-hexahydroazepino[4,5-b]indole, is achemical compound andparent structure of theibogalog group of compounds.[1][2][3] The ibogalogs that have been described includeibogaminalog,ibogainalog,noribogainalog,tabernanthalog,catharanthalog,fluorogainalog,LS-22925,PNU-22394, andPHA-57378, among others.[1][2][3][4][5] The ibogalogs, specifically ibogainalog and analogues, were first described in thescientific literature by 1968.[6][7]
The iboga alkaloids are long overdue for a detailed examination of their psychic effects in man. It is interesting that simplification of the iboga structure to give the hexahydroazepino[4,5-b]indoles (for example, 4.42) enhances the tryptamine-like properties, at least as far as tremorogenic activity is concerned, but also enhances the sedative effects. Thus, these compounds have chlorpromazine-like properties in both man and animals (Hester, Tang, Keesling, and Veldkamp, 1968).
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