Nicotine polacrilex

Clinical data
Trade names	Nicorette
License data	US DailyMed: Nicotine polacrilex
Routes of administration	By mouth
ATC code	None
Legal status
Legal status	UK: General sales list (GSL, OTC)[1][2] US: OTC[3]
Identifiers
UNII	6M3C89ZY6R

Nicotine polacrilex isnicotine bound to anion-exchange resin (polymethacrylic acid, such asAmberlite IRP64, Purolite C115HMR or Doshion P551).^[4] It is added togum and hard lozenges used fornicotine replacement therapy insmoking cessation, such as in theNicorette range of products. The use of the polymer as a delivery system maximizes the amount of nicotine released and absorbed by theoral mucosa. 80 to 90 percent of the nicotine released from the gum is absorbed by the mouth. Side effects of the gum include bad taste,nausea,dyspepsia, andstomatitis.

• Nicotine polacrilex at the U.S. National Library of MedicineMedical Subject Headings (MeSH)

Thismedical treatment–related article is astub. You can help Wikipedia byexpanding it.

• v
• t
• e

• Drugs not assigned an ATC code
• Over-the-counter drugs in the United States
• Smoking cessation
• Medical treatment stubs

• Articles with short description
• Short description matches Wikidata
• Use dmy dates from September 2025
• Short description is different from Wikidata
• Chemical articles without CAS registry number
• Articles without EBI source
• Chemical pages without ChemSpiderID
• Chemical pages without DrugBank identifier
• Articles without KEGG source
• Articles without InChI source
• Articles containing unverified chemical infoboxes
• All stub articles