The oxime is first converted to an O-sulfonate, for example atosylate by reaction withtosyl chloride. Addedbase forms acarbanion which displaces the tosylate group in anucleophilic displacement to anazirine and added water subsequently hydrolyses it to the aminoketone.
^P. W. Neber and A. v. Friedolsheim (1926). "Über eine neue Art der Umlagerung von Oximen".Justus Liebig's Annalen der Chemie.449 (1):109–134.doi:10.1002/jlac.19264490108.
^O'Brien, Connor (1 April 1964). "The Rearrangement of Ketoxime O-Sulfonates to Amino Ketones (The Neber Rearrangement)".Chemical Reviews.64 (2):81–89.doi:10.1021/cr60228a001.
