| Combination of | |
|---|---|
| Naproxen | NSAID |
| Esomeprazole | Proton pump inhibitor |
| Clinical data | |
| Trade names | Vimovo |
| AHFS/Drugs.com | Professional Drug Facts |
| Pregnancy category | |
| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| KEGG | |
Naproxen/esomeprazole, sold under the brand nameVimovo, is apain reliever medication in the form of a tablet for oral consumption, containingnaproxen, anonsteroidal anti-inflammatory drug (NSAID), and a delayed release formulation ofesomeprazole, a stomach acid–reducingproton-pump inhibitor (PPI).[2][3] It is produced byAstraZeneca.[4] Vimovo is USFood and Drug Administration approved for use againstosteoarthritis,rheumatoid arthritis, andankylosing spondylitis.[2] It is intended to decrease the risk ofgastric ulcers from treatment with NSAIDs.[2]
It is available as ageneric medication.[5] In 2020, it was the 390th most commonly prescribed medication in the United States, with more than 300,000 prescriptions.[6][7]
Vimovo was acquired by the Ireland-based company, Horizon Pharma on November 19, 2013. AstraZeneca retained "ex-U.S. rights to Vimovo".[3]
In a June 2017 article inThe Atlantic, journalist Marshall Allen wrote that, the cost of Aleve and Nexium, the two common medications" that became thespecialty drug Vimovo, was $40 a month. Horizon Pharma bills insurance companies $3,252 a month for Vimovo.[8] According toThe Atlantic, "since 2014, Horizon Pharma's net sales have been more than $455 million".[8]
After I was prescribed a brand-name drug I didn't need and given a coupon to cover the out-of-pocket costs, I discovered yet another reason why Americans pay too much for health care.
| pyrazolones / pyrazolidines | |
|---|---|
| salicylates | |
| acetic acid derivatives and related substances | |
| oxicams | |
| propionic acid derivatives (profens) |
|
| n-arylanthranilic acids (fenamates) | |
| COX-2 inhibitors (coxibs) | |
| other | |
| NSAID combinations | |
Key:underline indicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;†withdrawn drugs;‡veterinary use. | |
