
Naphthoylindoles are a class ofsynthetic cannabinoids.[1]
Behaving similarlyin vivo toendocannabinoids such asanandamide or2-arachidonoylglycerol (2-AG), naphthoylindoles can bind toendocannabinoidreceptors in animals, presenting asCB1 and/orCB2partial/fullagonists.
They have gained notoriety over the years for illicit usage and distribution inEurope andNorth America, typically marketed as "herbal incense blends."[2]