NESS-040C5

Clinical data
ATC code	none
Legal status
Legal status	CA: Schedule II
Identifiers
IUPAC name N-(2-isopropyl-5-methylcyclohexyl)-1-(4-methylbenzyl)-1,4-dihydrothieno[3',2':4,5]cyclopenta[1,2-c]pyrazole-3-carboxamide
CAS Number	1445751-90-5
PubChemCID	138402821
UNII	P6H2AAY2GE
CompTox Dashboard(EPA)	DTXSID201010004
Chemical and physical data
Formula	C27H33N3OS
Molar mass	447.64 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C=C1)=CC=C1CN2C3=C(CC4=C3SC=C4)C(C(NC5CC(C)CCC5C(C)C)=O)=N2

NESS-040C5 is a potentcannabinoidagonist which was developed for the treatment ofglaucoma.^[1] It has reasonable selectivity for theCB₂ receptor subtype, having a CB₂ affinity of 0.4nM, and 25x selectivity over the relatedCB₁ receptor.^[2]

• AB-FUBINACA
• NESS-0327
• SR-144,528

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