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| Clinical data | |
|---|---|
| Other names | N-t-Butyltryptamine; NtBT; NTBT |
| Routes of administration | Oral[1][2] |
| Drug class | Psychoactive drug |
| ATC code |
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| Pharmacokinetic data | |
| Duration of action | Unknown[1] |
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| CAS Number | |
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| Chemical and physical data | |
| Formula | C14H20N2 |
| Molar mass | 216.328 g·mol−1 |
| 3D model (JSmol) | |
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N-tert-Butyltryptamine (NtBT) is apsychoactive drug of thetryptamine family related topsychedelics likedimethyltryptamine (DMT).[1][2][3]
NtBT was briefly described byAlexander Shulgin in his bookTiHKAL (Tryptamines I Have Known and Loved).[1] According to Shulgin, NtBT is active at a dose of 5 to 20 mg or of ~20 mgorally.[1][2] He also said that he had heard that NtBT is extremelypotent whensmoked, but had not received any particulars or confirmed that.[1] Its effects included alightheadedintoxication described as a totally pleasant buzz, but nothing more profound than that.[1]
Shulgin has said that along withN-sec-butyltryptamine (NsBT), it is one of only twoN-mono-substituted tryptamines with known psychoactivity.[1] He also said thatN-mono-substituted tryptamines might beGHB-like intoxicants devoid of psychedelic effects.[1] However,N-methyltryptamine (NMT) has been reported to produce psychedelic effects.[1][4][5]
Analogues of NtBT includeN-methyltryptamine (NMT),N-ethyltryptamine (NET),N-isopropyltryptamine (NiPT),N-benzyltryptamine (NBnT),4-HO-DsBT, and4-HO-McPeT, among others.[1]
The tertiary-butyl analogue, NTBT, is the remaining mono-substituted tryptamine that just might have psychotropic potential. In the 5 to 20 milligram area, there is a light-headed intoxication that is a totally pleasant buzz, but nothing more profound than that. Wouldn't it be fascination of it turned out that all of the mono-tryptamines (the NRT's) were GHB-like intoxicants, and totally devoid of psychedelic activity. That would be a true challenge to the SAR crowd. I was told many years ago that NTBT was extremely potent when smoked, but I never received any particulars, and I must leave that as a baseless rumor.
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