| Names | |
|---|---|
| Preferred IUPAC name Ethyl 2-ethoxyquinoline-1(2H)-carboxylate | |
| Other names Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate | |
| Identifiers | |
3D model (JSmol) | |
| Abbreviations | EEDQ |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.036.728 |
| EC Number |
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| UNII | |
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| Properties | |
| C14H17NO3 | |
| Molar mass | 247.29 g/mol |
| Melting point | 62 to 67 °C (144 to 153 °F; 335 to 340 K) |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is an irreversible dopamine-receptor antagonist.[2]
EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.[3]
It is also an irreversibledopamine transporter (DAT)blockerin vitro, though it is ineffectivein vivo.[4]
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