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Morforex

From Wikipedia, the free encyclopedia
Non-marketed appetite suppressant drug
Pharmaceutical compound
Morforex
Clinical data
ATC code
  • None
Identifiers
  • 4-[2-[(α-Methylphenethyl)amino]ethyl]morpholine
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC15H24N2O
Molar mass248.370 g·mol−1
3D model (JSmol)
  • CC(Cc1ccccc1)NCCN2CCOCC2
  • InChI=1S/C15H24N2O/c1-14(13-15-5-3-2-4-6-15)16-7-8-17-9-11-18-12-10-17/h2-6,14,16H,7-13H2,1H3
  • Key:ISEKMORYCCULAL-UHFFFAOYSA-N

Morforex (INN;Bo 637), also referable to asN-morpholinoethylamphetamine, is ananorectic which was never marketed.[1][2]

It producesamphetamine as anactive metabolite.[3]

Synthesis

[edit]
Patent:[4]

Amphetamine is reacted with N-Chloroethylmorpholine [3240-94-6] in the presence of IPA solvent.

See also

[edit]

References

[edit]
  1. ^Ganellin CR, Triggle DJ (21 November 1996).Dictionary of Pharmacological Agents. CRC Press. pp. 1377–.ISBN 978-0-412-46630-4.
  2. ^World Health Organization (2000).International Nonproprietary Names (INN) for Pharmaceutical Substances. World Health Organization.ISBN 978-0-11-986227-0.
  3. ^Goodwin BL (10 November 2004).Handbook of Biotransformations of Aromatic Compounds. CRC Press. pp. 13–.ISBN 978-0-203-64196-5.
  4. ^FR 2199M, "N-morpholino-1 n-phénylisopropylamino-2 éthane [N-morpholino-1 N-phenylisopropylamino-2 ethane]", published 1963-12-09, assigned to Brevets Pharmaceutiques et Cosmetologiques 
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