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mir-589 microRNA precursor family

From Wikipedia, the free encyclopedia
RNA family
mir-589
Identifiers
Symbolmir-589
RfamRF00987
miRBase familyMIPF0000496
Other data
RNA typemicroRNA
DomainEukaryota;
PDB structuresPDBe

In molecular biologymir-589 microRNA is a shortRNA molecule.MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

Molecular targets

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miR-589 has been implicated in the regulation of antimicrobial targets inbovine lungalveolar macrophages, and alongside other miRNAs has been suggested to play a part in the immune response againstMycobacterium tuberculosis.[1] It has additionally been linked toHLA-G expression, having been found to target the3'UTR 14-base pair sequence region of the HLA-G gene.[2]

See also

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References

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  1. ^Xu G, Zhang Y, Jia H, Li J, Liu X, Engelhardt JG, et al. (2009). "Cloning and identification of microRNAs in bovine alveolar macrophages".Mol Cell Biochem.332 (1–2):9–16.doi:10.1007/s11010-009-0168-4.PMID 19507003.S2CID 10508574.
  2. ^Castelli EC, Moreau P, Oya e Chiromatzo A, Mendes-Junior CT, Veiga-Castelli LC, Yaghi L, et al. (2009). "In silico analysis of microRNAS targeting the HLA-G 3' untranslated region alleles and haplotypes".Hum Immunol.70 (12):1020–5.doi:10.1016/j.humimm.2009.07.028.PMID 19664672.

External links

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miRNA precursor families
1-100
101-200
201-300
301-400
401-500
501-600
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