 | |
| Names | |
|---|---|
| Preferred IUPAC name N,N′-Di(propan-2-yl)phosphorodiamidic fluoride | |
| Other names Bis(isopropylamino)fluorophosphine oxide; Isopestox | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.006.130 |
| EC Number |
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| KEGG | |
| UNII | |
| |
| |
| Properties | |
| C6H16FN2OP | |
| Molar mass | 182.179 g·mol−1 |
| Density | 1.2 |
| Melting point | 65 °C (149 °F; 338 K) |
| Boiling point | 125 °C (257 °F; 398 K) |
| 80 g/L | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards | Highly toxic |
| GHS labelling: | |
  | |
| Danger | |
| H301,H370 | |
| P260,P264,P270,P301+P310,P307+P311,P321,P330,P405,P501 | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Mipafox is a highly toxicorganophosphateinsecticide that is an irreversibleacetylcholinesterase inhibitor and is resistant tocholinesterase reactivators.[1] It was developed in the 1950s and is now believed to be no longer in use.[2]
There arecase reports of delayedneurotoxicity andparalysis due to acute exposure to mipafox.[3]
Phosphoryl chloride is first reacted withisopropylamine. The resulting product is then reacted withpotassium fluoride orammonium fluoride to produce mipafox.[4]
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