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Minkui Luo is a biochemist andprofessor of biochemistry atMemorial Sloan Kettering Cancer Center.^[1] His research interests include chemical biology and the study ofposttranslational modifications inepigenetic signaling, with an emphasis on proteinmethyltransferases.

Luo attended college atFudan University and earned his PhD in Bioorganic and Bioinorganic Chemistry in 2005 fromPrinceton University, where he worked in the lab of ProfessorJohn T. Groves.

From 2005 to 2008, Luo pursued postdoctoral studies at theAlbert Einstein College of Medicine in the lab of ProfessorVern Schramm. In 2008, Luo became a faculty member in the department ofMolecular Pharmacology and Chemistry atMemorial Sloan Kettering Cancer Center. His group has pioneered the use ofchemical genetic 'bump-hole' methodologies to identify the substrates of protein methyltransferases, an approach that requires engineering these enzymes to use a non-naturalS-adenosyl methionine analogue as a cofactor. Luo's lab also has contributed to the development of new chemical probes of protein methyltransferases, enabling their function to be probed in vitro and in cells.

Web of Science lists 77 publications authored by Luo inpeer-reviewedscientific journals that have been cited over 2000 times, leading to anh-index of 23.^[2] His lab's five most cited papers (>80 each) are:

1. Luo, Minkui (2012)."Current Chemical Biology Approaches to Interrogate Protein Methyltransferases".ACS Chemical Biology.7 (3):443–463.doi:10.1021/cb200519y.PMC 3306480.PMID 22220966.
2. Zheng, Weihong; Ibanez, Glorymar; Wu, Hong; Blum, Gil; Luo, Minkui; et al. (2012)."Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2".Journal of the American Chemical Society.134 (43):18004–18014.doi:10.1021/ja307060p.PMC 3504124.PMID 23043551.
3. Luo, Minkui (2018)."Chemical and Biochemical Perspectives of Protein Lysine Methylation".Chemical Reviews.118 (34):6656–6705.doi:10.1021/acs.chemrev.8b00008.PMC 6668730.PMID 29927582.
4. Wang, Rui; Zheng, Weihong; Yu, Haiqiang; Deng, Haiteng; Luo, Minkui (2011)."Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues".Journal of the American Chemical Society.133 (20):7648–7651.doi:10.1021/ja2006719.PMC 3104021.PMID 21539310.
5. Wang, Rui; Islam, Kabirul; Liu, Ying; Zheng, Weihong; Luo, Minkui; et al. (2013)."Profiling genome-wide chromatin methylation with engineered posttranslation apparatus within living cells".Journal of the American Chemical Society.135 (3):1048–1056.doi:10.1021/ja309412s.PMC 3582175.PMID 23244065.

Source:^[1]

• 2009 - The V Scholar Award, the V Foundation for Cancer Research
• 2010 -NIH Director's New Innovator Award (DP2)^[3]
• 2011 - Basil O'Connor Starter Scholar,March of Dimes Birth Defects Foundation
• 2014 - Clinical & Translational Science Center Novel Award,Weill Cornell Medical College
• 2015 -Eli Lilly Award in Biological Chemistry^[4]

• Fudan University alumni
• Princeton University alumni
• Memorial Sloan Kettering Cancer Center faculty
• Albert Einstein College of Medicine alumni
• Chinese molecular biologists
• Living people

• BLP articles lacking sources from January 2023
• All BLP articles lacking sources
• Articles with hCards
• Year of birth missing (living people)