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| ECHA InfoCard | 100.016.147 |
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| Formula | C12H11I3N2O4 |
| Molar mass | 627.943 g·mol−1 |
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Metrizoic acid is apharmaceutical drug that was used as aniodinated contrast medium forX-ray imaging. Its uses includedangiography[1] (imaging of blood vessels andheart chambers) andurography[2] (imaging of theurinary tract), but it has been discontinued, at least in the US.[3]
It was used in form of its salts,metrizoates. Due to its highosmolality, metrizoic acid had a risk of inducing allergic reactions higher than that of lower osmolar contrast media.[4]
The iodine content of metrizoate ranged from 370 mg/ml to 440 mg/ml, with osmolarity has high as 2100 mOsm/kg. The viscosity is 3.4 cP at 37 degree Celsius (human body temperature).[5]
Side effects of metrizoate are: urticaria, headache, nausea, vomiting, dizziness, and hypotension. Other side effects include minor electrocardiographic changes such as tachycardia, bradycardia, and inversion of T waves.[6]
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