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Methyldiazinol

From Wikipedia, the free encyclopedia
Anabolic steroid
Pharmaceutical compound
Methyldiazinol
Clinical data
Other namesMethyldiazirinol; 3,3-Azo-17α-methyl-5α-dihydrotestosterone; 3,3-Azo-17α-methyl-DHT; 3,3-Azo-17α-methyl-5α-androstan-17β-ol; 3-Azi-17α-methyl-5α-androstan-17β-ol
Routes of
administration
By mouth
Drug classAndrogen;Anabolic steroid
Identifiers
  • (5S,8R,9S,10S,13S,14S,17S)-10,13,17-Trimethylspiro[2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,3'-diazirine]-17-ol
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC20H32N2O
Molar mass316.489 g·mol−1
3D model (JSmol)
  • C[C@]12CCC3(C[C@@H]1CC[C@@H]4[C@@H]2CC[C@]5([C@H]4CC[C@]5(C)O)C)N=N3
  • InChI=LMNFACKYKJIJHJ-PHFHYRSDSA-N
  • Key:1S/C20H32N2O/c1-17-10-11-20(21-22-20)12-13(17)4-5-14-15(17)6-8-18(2)16(14)7-9-19(18,3)23/h13-16,23H,4-12H2,1-3H3/t13-,14+,15-,16-,17-,18-,19-/m0/s1

Methyldiazinol (also known as3,3-azo-17α-methyl-5α-dihydrotestosterone,3-azi-17α-methyl-DHT, or3,3-azo-17α-methyl-5α-androstan-17β-ol) is asynthetic andorally activeandrogen/anabolic steroid (AAS) which was never marketed.[1][2] It is a17α-methylatedderivative ofdihydrotestosterone (DHT); specifically, it is the C3azi (i.e., 3,3-azo)analogue ofmestanolone (17α-methyl-DHT).[1][2] The drug has been found to possess a high ratio and dissociation ofmyotrophic toandrogenic activity; relative tomethyltestosterone, its ratio was 15 (3:0.2), among the highest observed.[1][2]

See also

[edit]

References

[edit]
  1. ^abcKochakian CD (6 December 2012).Anabolic-Androgenic Steroids. Springer Science & Business Media. p. 385.ISBN 978-3-642-66353-6.Methyldiazinol: 3-Azi-17-methyl-5α-androstan-17β-ol: The 3-azi derivative of methandrostanolone was noted by CHURCH et al. (1965) to have a wide myotrophic:androgenic dissociation (3: 0.2) 15 relative to methyltestosterone orally, among the highest noted.
  2. ^abcChurch RF, Kende AS, Weiss MJ (1965). "Diazirines. I. Some Observations on the Scope of the Ammonia-Hydroxylamine-O-sulfonic Acid Diaziridine Synthesis. The Preparation of Certain Steroid Diaziridines and Diazirines".Journal of the American Chemical Society.87 (12):2665–2671.Bibcode:1965JAChS..87.2665C.doi:10.1021/ja01090a025.ISSN 0002-7863.
ARTooltip Androgen receptor
Agonists
SARMsTooltip Selective androgen receptor modulator
Antagonists
GPRC6A
Agonists
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