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Methafurylene

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Methafurylene
Clinical data
ATC code
  • none
Identifiers
  • N-(2-Furylmethyl)-N,N-dimethyl-N-pyridin-2-ylethane-1,2-diamine
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC14H19N3O
Molar mass245.326 g·mol−1
3D model (JSmol)
  • CN(C)CCN(CC1=CC=CO1)C2=CC=CC=N2
  • InChI=1S/C14H19N3O/c1-16(2)9-10-17(12-13-6-5-11-18-13)14-7-3-4-8-15-14/h3-8,11H,9-10,12H2,1-2H3
  • Key:LUQHAHRMUPOTQK-UHFFFAOYSA-N
  (verify)

Methafurylene is anantihistamine andanticholinergic.[1] Methafurylene is commonly used to relieve symptoms of allergies such as sneezing, itching, and runny nose (Sweetman, 2009).

References

[edit]
  • Sweetman, S. C. (Ed.). (2009).Martindale: The Complete Drug Reference (36th ed.). Pharmaceutical Press.

See also

[edit]

References

[edit]
  1. ^Orcutt JA, Prytherch JP (August 1950). "Pharmacology of N-(2-furfuryl)-N-(2-pyridyl)-N',N'-dimethylethylenediamine fumarat (methafurylene fumarate). I. Antihistaminic properties of this compound and its 5-chloro and 5-bromo derivatives".The Journal of Pharmacology and Experimental Therapeutics.99 (4:1):479–87.PMID 15437326.


mAChRsTooltip Muscarinic acetylcholine receptors
Agonists
Antagonists
Precursors
(andprodrugs)
nAChRsTooltip Nicotinic acetylcholine receptors
Agonists
(andPAMsTooltip positive allosteric modulators)
Antagonists
(andNAMsTooltip negative allosteric modulators)
Precursors
(andprodrugs)
H1
Agonists
Antagonists
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists


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