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Cysteine methyl ester

From Wikipedia, the free encyclopedia
(Redirected fromMecysteine)
Chemical compound
Pharmaceutical compound
Cysteine methyl ester
Clinical data
Other namesMethyl L-cysteinate
AHFS/Drugs.comInternational Drug Names
Identifiers
  • methyl (2R)-2-amino-3-sulfanylpropanoate
CAS Number
PubChemCID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.017.842Edit this at Wikidata
Chemical and physical data
FormulaC4H9NO2S
Molar mass135.18 g·mol−1
3D model (JSmol)
  • COC(=O)C(CS)N
  • InChI=1S/C4H9NO2S/c1-7-4(6)3(5)2-8/h3,8H,2,5H2,1H3/t3-/m0/s1 checkY
  • Key:MCYHPZGUONZRGO-VKHMYHEASA-N checkY

Cysteine methyl ester is theorganic compound with the formula HSCH2CH(NH2)CO2CH3. It is a white solid substance, known as the methylester of theamino acid,cysteine.

Uses

[edit]

Under the brand nameMecysteine, cysteine methyl ester is a commercial drug formucolytic activity.[1] The compound has an ability to break down or lower the viscosity of mucin-containing secretions or components of fluids by chronic and acute respiratory disorders. The drug is sold under the commercial names Delta in Paraguay, and Pectite and Zeotin in Japan.[2]

Cysteine methyl ester is also used as a building block for synthesis of N,S-heterocycles.[3][4]

References

[edit]
  1. ^Page CP (2018)."Respiratory System: Mucolytics". In Datta ST, Xiu P (eds.).Pharmacology (Fifth ed.). Philadelphia, PA: Elsevier. p. 40.ISBN 978-0-7020-7345-8.
  2. ^"Mecysteine".Drugs.com.
  3. ^Tanaka T, Nakashima T, Ueda T, Tomii K, Kouno I (June 2007)."Facile discrimination of aldose enantiomers by reversed-phase HPLC".Chemical & Pharmaceutical Bulletin.55 (6):899–901.doi:10.1248/cpb.55.899.hdl:10069/14910.PMID 17541189.
  4. ^Hamada Y, Shibata M, Sugiura T, Kato S, Shioiri T (1987). "New methods and reagents in organic synthesis. 67. A general synthesis of derivatives of optically pure 2-(1-aminoalkyl)thiazole-4-carboxylic acids".The Journal of Organic Chemistry.52 (7):1252–1255.doi:10.1021/jo00383a014.
Expectorants
Mucolytics
Cough suppressants
Opium alkaloids,
opioids,
and derivatives
Other
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