English medical scientist and immunologist
Sir Mark Jeremy Walport (born 25 January 1953[ 3] medical scientist and was theGovernment Chief Scientific Adviser in the United Kingdom from 2013 to 2017[ 5] [ 6] [ 7] [ 8] [ 9] [ 10] [ 11] [ 12] UK Research and Innovation (UKRI) from 2017[ 13] [ 14] The Royal Society (jointly withAlison Noble ).[ 15]
Walport is the son of ageneral practitioner and was born in London. He was educated atSt Paul's School, London ,[ 3] Clare College, Cambridge , and completed his clinical training atHammersmith ,Guy's andBrompton Hospitals in London.[ 16] [ 17] complement receptors under the supervision ofPeter Lachmann in 1986 at theUniversity of Cambridge .[ 18]
Career and research [ edit ] Previously Walport was Director of theWellcome Trust from 2003 to 2013.[ 4] Imperial College London ,[ 16] rheumatic diseases .[ 19] [ 20] [ 21] [ 22] [ 23] [ 24] [ 25] [ 26]
Walport was the eleventhGovernment Chief Scientific Adviser from 2013 to 2017, succeeding SirJohn Beddington .
It was announced in February 2017 that Mark Walport is now Chief Executive ofUK Research and Innovation (UKRI) .[ 13]
Walport wasknighted in the2009 New Year Honours list for services to medical research. He was elected an HonoraryFellow of the Royal Society of Edinburgh (FRSE) in 2017[ 27] Fellow of the Royal Society (FRS) in 2011.[ 1] [ 16]
Mark Walport has an overwhelming case for election both for his earlier scientific work on the immunology ofsystemic LE and the role of complement and of defectiveapoptosis in itspathogenesis ; and, as a general candidate, for his achievements as head of medicine at the Hammersmith Campus of Imperial College and since 2003 as Director of the Wellcome Trust. In the latter role he has provided national and international leadership at the highest level on biomedical research and policy issues and is widely recognised as a world leader in the promotion of biomedical science.[ 1]
Walport is married to Dr Julia Walport MBE (nee Neild), master of theWorshipful Society of Apothecaries . Lady Walport is a trustee of the Amber Trust and of Ealing Youth Orchestra. She was made MBE in the2024 New Year Honours .
^a b c Anon (2011)."Sir Mark Walport" .Royal Society . Retrieved5 July 2012 . "All text published under the heading 'Biography' on Fellow profile pages is available underCreative Commons Attribution 4.0 International License ." --Royal Society Terms, conditions and policies at theWayback Machine (archived 2016-11-11)
^ Reed, Tanya (11 July 2003)."Wellcome to a new beginning" .Reporter: The newspaper of Imperial College London . No. 131. ^a b c d e f Anon (2015)."Walport, Sir Mark (Jeremy)" Who's Who Oxford University Press ed.). A & C Black.doi :10.1093/ww/9780199540884.013.U38753 . (Subscription orUK public library membership required.) ^a b Vogel, Gretchen (2003)."United Kingdom: Mark Walport to Take Reins at Wellcome Trust" .Science .299 (5608): 803a–.doi :10.1126/science.299.5608.803a PMID 12574591 .S2CID 70581694 . ^a b Callaway, Ewen (2012)."Britain names next chief science adviser: Immunologist Mark Walport, head of one of the world's largest biomedical charities, will take on role in 2013" .Nature .487 (7405): 20.doi :10.1038/487020a PMID 22763530 . ^ Mayor, S. (2012). "Mark Walport will be next UK government chief scientific adviser, cabinet office announces".BMJ .345 e4621.doi :10.1136/bmj.e4621 .PMID 22767620 .S2CID 11529948 . ^ Kain, K. H. (2010)."Funding scientific discovery: An interview with Sir Mark Walport" .Disease Models & Mechanisms .3 (5– 6):265– 267.doi :10.1242/dmm.005710 PMID 20427555 . ^ Anon (2012)."Good advice: The UK government's latest appointment offers hope for British science" .Nature .487 (7405):5– 6.doi :10.1038/487005b PMID 22763508 . ^ Gibney, Elizabeth (29 June 2012)."New chief scientific adviser announced" .Times Higher Education ^ Mark Walport's publications indexed by theScopus bibliographic database.(subscription required) ^ Sir Mark Walport in conversation with David Cleevely, Centre for Science and Policy (CSaP) University of Cambridge YouTube ^ Boulton, G.; Rawlins, M.; Vallance, P.; Walport, M. (2011). "Science as a public enterprise: The case for open data".The Lancet .377 (9778):1633– 1635.doi :10.1016/S0140-6736(11)60647-8 .PMID 21571134 .S2CID 3048048 . ^a b "Sir Mark Walport will lead UK Research and Innovation" .www.gov.uk (Press release). 2 February 2017. Retrieved4 July 2017 .^ "Dominic Cummings' science obsession: based on fact or fiction?" .Times Higher Education (THE) . 16 October 2019. Retrieved25 November 2019 .^ "Council" .The Royal Society . Retrieved4 July 2023 .^a b c "Dr Sir Mark Walport" .Debrett's . Retrieved14 February 2012 .^ Morris, K. (2003). "Mark Walport".The Lancet 362 (9382):498– 499.doi :10.1016/S0140-6736(03)14090-1 .PMID 12927451 .S2CID 10861093 . ^ Walport, Mark Jeremy (1986).The biology of complement receptors OCLC 59761908 .EThOS uk.bl.ethos.383309 . ^ "Mark Walport, PhD, MB. BChir., Member, Scientific Board" .Grand Challenges in Global Health . Archived fromthe original on 27 September 2013. Retrieved14 February 2012 .^ Walport, M. ; Foulkes, I.; Weissberg, P.; Morgan, D.; Nebhrajani, S. (2012)."Medical research: No catch to UK charity funding" .Nature .482 (7385): 308.Bibcode :2012Natur.482..308W .doi :10.1038/482308a PMID 22337042 .^ Collins, P. Y.; Patel, V.; Joestl, S. S.; March, D.; Insel, T. R.; Daar, A. S.; Scientific Advisory Board the Executive Committee of the Grand Challenges on Global Mental Health; Bordin, I. A.; Anderson, E. J.; Dhansay, M.; Phillips, C.; Shurin, R. I.; Walport, W.; Ewart, Y.; Savill, S. E.; Bordin, K.; Costello, S.; Durkin, S.; Fairburn, A.; Glass, A.; Hall, A.; Huang, M. M.; Hyman, V.; Jamison, B. J.; Kaaya, S.; Kapur, P. A.; Kleinman, D. J.; Ogunniyi, W.; Otero-Ojeda, M. A.; Poo, W.; Ravindranath, A. (2011)."Grand challenges in global mental health" .Nature .475 (7354):27– 30.doi :10.1038/475027a .PMC 3173804 PMID 21734685 . ^ Yamada, T.; Dautry, A.;Walport, M. (2008)."Ready for avian flu?" .Nature .454 (7201): 162.Bibcode :2008Natur.454..162Y .doi :10.1038/454162a PMID 18615064 .S2CID 205039550 . ^ Pickering, M. C.; Warren, J.; Rose, K. L.; Carlucci, F.; Wang, Y.;Walport, M. J. ; Cook, H. T.; Botto, M. (2006)."Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice" .Proceedings of the National Academy of Sciences .103 (25):9649– 9654.Bibcode :2006PNAS..103.9649P .doi :10.1073/pnas.0601094103 PMC 1476693 PMID 16769899 . ^ Brown, J. S.; Hussell, T.; Gilliland, S. M.; Holden, D. W.; Paton, J. C.; Ehrenstein, M. R.;Walport, M. J. ; Botto, M. (2002)."The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice" .Proceedings of the National Academy of Sciences .99 (26):16969– 16974.Bibcode :2002PNAS...9916969B .doi :10.1073/pnas.012669199 PMC 139253 PMID 12477926 . ^ Botto, M.; Fong, K. Y.; So, A. K.; Barlow, R.; Routier, R.; Morley, B. J.;Walport, M. J. (1992)."Homozygous hereditary C3 deficiency due to a partial gene deletion" .Proceedings of the National Academy of Sciences of the United States of America .89 (11):4957– 4961.Bibcode :1992PNAS...89.4957B .doi :10.1073/pnas.89.11.4957 PMC 49207 PMID 1350678 . ^ Taylor, P. R.; Carugati, A.; Fadok, V. A.; Cook, H. T.; Andrews, M.; Carroll, M. C.;Savill, J. S. ; Henson, P. M.; Botto, M.; Walport, M. J. (2000)."A Hierarchical Role for Classical Pathway Complement Proteins in the Clearance of Apoptotic Cells in Vivo" .Journal of Experimental Medicine .192 (3):359– 366.doi :10.1084/jem.192.3.359 .PMC 2193213 PMID 10934224 . ^ "RSE Welcomes 60 New Fellows" (Press release).Royal Society of Edinburgh . 15 February 2017. Retrieved28 March 2017 .text available under theCC BY 4.0 license.
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