| Malacoherpesviridae | |
|---|---|
| Virus classification | |
| (unranked): | Virus |
| Realm: | Duplodnaviria |
| Kingdom: | Heunggongvirae |
| Phylum: | Peploviricota |
| Class: | Herviviricetes |
| Order: | Herpesvirales |
| Family: | Malacoherpesviridae |
| Genera | |
See text | |
Malacoherpesviridae is a family ofDNA viruses in the orderHerpesvirales.Molluscs serve as natural hosts, making members of this family the only known herpesviruses to infect invertebrates. There are currently only two species recognised in this family, both classified into separate genera. Disease associated with this family includes sporadic episodes of high mortality among larvae and juveniles.[1][2][3] The family nameMalacoherpesviridae is derived fromGreek word 'μαλακός (malacos) meaning 'soft' and from Greek word 'μαλάκιον (malakion) meaning 'mollusc'.[3]
Acute viral necrosis virus, which affectsscallops such asChlamys farreri, appears to be a variant of Ostreid herpesvirus 1.[8]
Viruses inMalacoherpesviridae are enveloped, with icosahedral and spherical to pleomorphic geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 134kb in length.[1]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Aurivirus | Spherical pleomorphic | T=16 | Enveloped | Linear | Monopartite |
| Ostreavirus | Spherical pleomorphic | T=16 | Enveloped | Linear | Monopartite |
Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. DNA templated transcription is the method of transcription. Molluscs serve as the natural host.[1]Malacoherpesviridae may have the ability toinfect across species, a feature not typically observed invertebrateherpesviruses. This ability appears to be restricted to related mollusc species.[4]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Aurivirus | Haliotidae molluscs | B-lymphocytes | Glycoprotiens | Budding | Nucleus | Nucleus | Sex; saliva |
| Ostreavirus | Molluscs | B-lymphocytes | Glycoprotiens | Budding | Nucleus | Nucleus | Sex; saliva |
This article incorporates CC-BY-2.0 text from the reference[4]