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MFSD7

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
SLC49A3
Identifiers
AliasesSLC49A3, LP2561, major facilitator superfamily domain containing 7, solute carrier family 49 member 3, MFSD7
External IDsMGI:2442629;HomoloGene:49990;GeneCards:SLC49A3;OMA:SLC49A3 - orthologs
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for SLC49A3
Genomic location for SLC49A3
Band4p16.3Start681,829bp[1]
End689,441bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for SLC49A3
Genomic location for SLC49A3
Band5|5 FStart108,588,920bp[2]
End108,596,966bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • apex of heart

  • left testis

  • right testis

  • monocyte

  • right lobe of thyroid gland

  • granulocyte

  • minor salivary glands

  • left lobe of thyroid gland

  • body of stomach

  • right auricle of heart
Top expressed in
  • white adipose tissue

  • zone of skin

  • colon

  • lip

  • ileum

  • esophagus

  • jejunum

  • duodenum

  • urinary bladder

  • muscle tissue
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

84179

243197

Ensembl

ENSG00000169026

ENSMUSG00000029490

UniProt

Q6UXD7

Q8CE47

RefSeq (mRNA)

NM_001294341
NM_001294342
NM_032219

NM_172883
NM_001359977

RefSeq (protein)
NP_001281270
NP_001281271
NP_115595
NP_001364988
NP_001364989

NP_001364990
NP_001364991

NP_766471
NP_001346906

Location (UCSC)Chr 4: 0.68 – 0.69 MbChr 5: 108.59 – 108.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Major facilitator superfamily domain containing 7 is aprotein that in humans is encoded by the MFSD7gene.[5]

MFSD7is anatypical SLC,[6][7] thus a predictedSLC transporter. It clusters phylogenetically to the Atypical MFS Transporter family 5(AMTF5) and theSLC49 family.

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000169026Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000029490Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^"Entrez Gene: Major facilitator superfamily domain containing 7".
  6. ^Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017)."Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression".Open Biology.7 (9) 170142.doi:10.1098/rsob.170142.PMC 5627054.PMID 28878041.
  7. ^Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters".Trends in Pharmacological Sciences.38 (3):305–315.doi:10.1016/j.tips.2016.11.008.PMID 27939446.
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