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MDM1EA

From Wikipedia, the free encyclopedia

Pharmaceutical compound
MDM1EA
Clinical data
Other namesN-Methyl-1-(3,4-methylenedioxyphenyl)-1-ethanamine; MDM1EA; α,N-Dimethyl-3,4-methylenedioxybenzylamine; α,N-DMMDBA; α,N-Dimethylpiperonylamine; α,N-Dimethyl-1,3-benzodioxole-5-methanamine
Identifiers
  • 1-(1,3-benzodioxol-5-yl)-N-methylethanamine
CAS Number
PubChemCID
ChemSpider
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC10H13NO2
Molar mass179.219 g·mol−1
3D model (JSmol)
  • CC(C1=CC2=C(C=C1)OCO2)NC
  • InChI=1S/C10H13NO2/c1-7(11-2)8-3-4-9-10(5-8)13-6-12-9/h3-5,7,11H,6H2,1-2H3
  • Key:USAUUVXZKYYZIL-UHFFFAOYSA-N

N-Methyl-1-(3,4-methylenedioxyphenyl)-1-ethanamine (MDM1EA), also known asα,N-dimethyl-3,4-methylenedioxybenzylamine (α,N-DMMDBA) or asα,N-dimethylpiperonylamine, is anentactogen-likedrug of thebenzylamine family related toMDMA.[1][2][3] It is theanalogue of MDMA in which theside chain has been shortened by onecarbonatom.[1][2][3]

The drug has been found to be a weakserotonin reuptake inhibitor and partially substituted for MDMA in rodentdrug discrimination tests at the highest assessed doses.[1][2][4][3] The effects of α,N-DMMDBA in humans are unknown.[1]

It is not acontrolled substance in theUnited States as of 2011.[1]

Homo-MDMA (HMDMA), an analogue of MDMA in which the side chain was extended by one carbon atom, has also beensynthesized and studied.[2][3] It partially substituted for MDMA similarly to MDM1EA.[2][3]

See also

[edit]

References

[edit]
  1. ^abcdeShulgin A, Manning T, Daley PF (2011)."#45. α,N-DMMDBA".The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley, CA: Transform Press. pp. 80–81.ISBN 978-0-9630096-3-0.OCLC 709667010.
  2. ^abcdeTrachsel D, Lehmann D, Enzensperger C (2013).Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German). Solothurn: Nachtschatten-Verlag. p. 594.ISBN 978-3-03788-700-4.OCLC 858805226. Retrieved29 January 2025.
  3. ^abcdeBronson ME, Barrios-Zambrano L, Jiang W, Clark CR, DeRuiter J, Newland MC (December 1994). "Behavioral and developmental effects of two 3,4-methylenedioxymethamphetamine (MDMA) derivatives".Drug and Alcohol Dependence.36 (3):161–166.doi:10.1016/0376-8716(94)90141-4.PMID 7889806.
  4. ^Hashimoto K, Maeda H, Goromaru T (September 1992). "Antagonism of 3,4-methylenedioxymethamphetamine-induced neurotoxicity in rat brain by 1-piperonylpiperazine".European Journal of Pharmacology.228 (2–3):171–174.doi:10.1016/0926-6917(92)90027-a.PMID 1280228.

External links

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