American computer scientist
Louis Hodes (June 19, 1934 – June 30, 2008) was an Americanmathematician ,computer scientist , andcancer researcher .[ 1]
Early life and computer science work [ edit ] Louis Hodes got hisBachelor of Science (B.S.) from thePolytechnic Institute of Brooklyn . He got hisDoctor of Philosophy (Ph.D.) from theMassachusetts Institute of Technology (MIT) in 1962, underHartley Rogers with a thesis oncomputability .[ 1] WithJohn McCarthy , in the late 1950s and early 1960s, he helped produce the earliest implementations of the programming languageLisp ,[ 2] and underMarvin Minsky he did early research on visualpattern recognition in Lisp.[ 3] [ 4] [ 5] He is also credited by some with the idea, and an initial implementation, oflogic programming .[ 1] [ 6] [ 7] [ 8]
In 1966 he moved into cancer-related research, specifically atNational Institutes of Health and later theNational Cancer Institute where he turned his interest in visual pattern recognition tomedical imaging applications.[ 1] [ 9] He also worked on efficient algorithms for screening chemical compounds for studying chemical carcinogenesis.[ 1] [ 10] [ 11] [ 12] [ 13] [ 14] His work on models of clustering for chemical compounds was pronounced a "milestone" by the Developmental Therapeutics Program of the National Cancer Institute, for "revolutioniz[ing] the selection of compounds of interest by measuring the novelty of a chemical structure by comparing it to known compounds."[ 15]
^a b c d e "Obituaries: Louis Hodes: Scientist" .The Washington Post . 1 Aug 2008.^ McCarthy, J. ; Brayton, R.; Edwards, D.;Fox, P. ;Hodes, L. ;Luckham, D. ; Maling, K.;Park, D. ;Russell, S. (March 1960),LISP I Programmers Manual (PDF) ,Boston ,Massachusetts : Artificial Intelligence Group,M.I.T. Computation Center and Research Laboratory, archived fromthe original (PDF) on 2010-07-17, retrieved11 May 2010 ^ MIT research summary report, ch.XVI: Artificial Intelligence, p.166 ^ "Artificial Intelligence Project – RLE and MIT Computation Center Memo 18 – Some results from a pattern recognition program using LISP", undated memo,[1] ^ Hodes, L. "Machine Processing of Line Drawings", M.I.T. Lincoln Laboratory Report, 54G-0028 March 1961 ^ Minker, Jack (1988)."Perspectives in deductive databases" .The Journal of Logic Programming .5 :33– 60.doi :10.1016/0743-1066(88)90006-4 .^ Lobo, Jorge; Minker, Jack; Rajasekar, Arcot (1992).Foundations of Disjunctive Logic Programming . MIT Press. p. 19.ISBN 978-0-262-12165-1 . ^ Hodes, L. Hodes (1966)."Programming languages, logic and cooperative games" .Proceedings of the first ACM symposium on Symbolic and algebraic manipulation . pp. 1201– 1217. ^ "A programming system for the on-line analysis of biomedical images",Communications of the ACM v.13, #5 (May 1970) pp. 279–283ISSN 0001-0782 [2] ^ Feldman, Alfred; Hodes, Louis (1979)."Substructure Search with Queries of Varying Specificity" .Journal of Chemical Information and Computer Sciences .19 (3):125– 129.doi :10.1021/ci60019a003 . ^ Hodes, Louis (1986)."A two-component approach to predicting antitumor activity from chemical structure in large-scale screening" .Journal of Medicinal Chemistry .29 (11):2207– 2212.doi :10.1021/jm00161a013 .PMID 3783583 . ^ Hodes, Louis (1989)."Clustering a large number of compounds. 1. Establishing the method on an initial sample" .Journal of Chemical Information and Computer Sciences .29 (2):66– 71.doi :10.1021/ci00062a004 .PMID 2745581 . ^ Hodes, Louis (1981)."Selection of molecular fragment features for structure-activity studies in antitumor screening" .Journal of Chemical Information and Computer Sciences .21 (3):132– 136.doi :10.1021/ci00031a004 .PMID 7287834 . ^ Hodes, Louis (1981)."Computer-aided selection of compounds for antitumor screening: Validation of a statistical-heuristic method" .Journal of Chemical Information and Computer Sciences .21 (3):128– 132.doi :10.1021/ci00031a003 .PMID 7287833 . ^ "Developmental Therapeutics Program (DTP)" .National Cancer Institute, Division of Cancer Treatment and Diagnosis . Retrieved2024-10-31 .