Lethal injection is the practice of injecting one or more drugs into a person by a government for the express purpose of causing immediate death. WhileNazi Germany was known to execute enemies of the state using an injection of lethal drugs, the first country to legalize and formally implement what is referred to today as lethal injectionwas the United States. The state ofTexas adopted it as its form on capital punishment in 1977 and executed the first person by it,Charles Brooks Jr., in 1982.^[1] The practice was subsequently adopted by the other US states using capital punishment.^[2] As of 2025, the method is available for use by 27 US states, as well as by their federal government and military.^[3]

Lethal injection was proposed and adopted on the grounds it was more humane than the methods of execution in place at the time, such as theelectric chair andgas chamber.^[2] Opponents of lethal injection reject this argument, noting multiple cases where executions have been either painful, prolonged, or both.^[4][5][6] According to theDeath Penalty Information Center, lethal injections have the highest rate of botched executions of any method used in the US, with 7.12% of executions using this method between 1982 and 2010 considered to have not gone according to plan.^[7][8] A study published inThe Lancet in 2005 found that in 43% of cases of lethal injection, the blood level ofhypnotics was insufficient to guarantee unconsciousness.^[9] TheSupreme Court of the United States ruled 7–2 in 2008 (Baze v. Rees), 5–4 in 2015 (Glossip v. Gross), and 5–4 in 2019 (Bucklew v. Precythe) that lethal injection does not constitutecruel and unusual punishment.^[10][11]

Lethal injection was also adopted as amethod of execution by Guatemala in 1996,China in 1997, thePhilippines in 1999,Thailand in 2003,Taiwan in 2005,Vietnam in 2013,^[12] theMaldives in 2014^[13] andNigeria in 2015.^[14] The Philippines abolished the death penalty in 2006.^[15] While the death penalty still exists in the Maldives and Guatemala, no executions have been carried out there since 1954 and 2000 respectively.^[16] Taiwan has never actually used the method, instead carrying out all executions by single gunshot.^[17] The US and China are the two biggest users of this method of execution. The US had executed 1,448 people via lethal injection as of August 2025.^[3] The number of people executed annually in China is thought to surpass all other countries combined, though the actual number is a state secret,^[18] and the percentage of people executed via lethal injection and the other method of execution used there,firing squad, is also unclear.^[19]

This alphabetical list features notable executions up to December 2025, and only those where lethal injection can be reliably sourced to be the method used. The criterion for notability is either an article on the individual, the crime they were executed for, or a court case related to their execution, in theEnglish Wikipedia.