This is a list of computersoftware which is made forbioinformatics and released underopen-source software licenses with articles in Wikipedia.
| Software | Description | Platform | License | Developer |
|---|---|---|---|---|
| .NET Bio | Language-neutral toolkit built using the Microsoft 4.0 .NET Framework to help developers, researchers, and scientists | .NET Framework | Apache | Collaborative project |
| AMPHORA | Metagenomics analysis software | Linux | GPL | Jonathan Eisen |
| Anduril | Component-basedworkflow framework for data analysis | Linux,macOS,Windows | GPL | University of Helsinki |
| Apache Taverna | Written inJava | Linux,macOS,Windows | Apache License 2.0 | Apache Software Foundation,myGrid |
| Ascalaph Designer | Computer program for general purpose molecular modelling for molecular design and simulations. | Windows | GPLv2 | Agile Molecule |
| AutoDock | Suite of automated docking tools | Linux,Mac OS X,SGI IRIX, andWindows | GPL | Scripps Research |
| Avogadro | C++ (Qt) based molecule editor and visualizer for in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas. | Linux,macOS,Unix,Windows | 3-ClauseBSD License | Open Chemistry Project |
| BEDtools | "Genome arithmetic"—manipulation of coordinate sets and the extraction of sequences from a BED file. | Linux | MIT | QuinlanLab,University of Utah |
| Bioclipse | Visual platform forchemo- andbioinformatics based on theEclipse Rich Client Platform (RCP) | Linux,macOS,Windows[1] | Eclipse Public | The Bioclipse Project |
| Bioconductor | R (programming language) language toolkit | Linux,macOS,Windows | Artistic 2.0 | Fred Hutchinson Cancer Research Center |
| BioJava | Java library functions for manipulating sequences, protein structures, file parsers, CORBA interoperability, Distributed Annotation System (DAS), access to AceDB, dynamic programming, and simple statistical routines | Linux,macOS,Windows | LGPL v2.1 | Open Bioinformatics Foundation |
| BioJS | JavaScript library of components to visualize biological data | Web browser | Apache | BioJS Community |
| BioMOBY | Registry ofweb services | Web browser | Artistic | Open Bioinformatics Foundation |
| BioPerl | Perl language toolkit | Cross-platform | Artistic,GPL | Open Bioinformatics Foundation |
| BioPHP | PHP language toolkit with classes for DNA and protein sequence analysis, alignment, database parsing, and other bioinformatics tools | Cross-platform | GPL v2 | Open Bioinformatics Foundation |
| Biopython | Python language toolkit | Cross-platform | Biopython[2] | Open Bioinformatics Foundation |
| BioRuby | Ruby language toolkit | Linux,macOS,Windows[3] | GPL v2 orRuby | Open Bioinformatics Foundation |
| BLAST | Algorithm and program for comparing primary biological sequence information, including DNA and protein sequences. | Cross-platform | Public domain | National Center for Biotechnology Information |
| CP2K | Perform atomistic simulations of solid state, liquid, molecular and biological systems, written in Fortran 2003. | Linux,macOS,Windows | GPL andLGPL | Free open source GNU GPLv2 or later |
| EMBOSS | Suite of packages for sequencing, searching, etc. written inC | Linux,macOS,Unix,Windows[4] | GPL andLGPL | Collaborative project |
| Galaxy | Scientific workflow anddata integration system | Unix-like | Academic Free | Collaborative project |
| GenePattern | Scientific workflow system that provides access to hundreds of genomic analysis tools | Unix-like (public server);Linux,macOS,Windows | MIT | Broad Institute,UC San Diego |
| Geworkbench | Genomicdata integration platform | Linux,macOS,Windows | GeWorkbench License[5] | Columbia University |
| GMOD | Toolkit to address many common challenges at biological databases | Unix-like (server),Web browser (client) | Varies depending on tool | Collaborative project |
| GenGIS | Application that allows combining digital map data with information about biological sequences collected from the environment | Windows,macOS | GPL | Collaborative project |
| GenoCAD | A computer-assisted design (CAD) tool for synthetic biology, used to design genetic constructs based on grammar rules. | Linux,macOS,Windows | Apache License 2.0 | GenoCAD Team (Virginia Bioinformatics Institute) |
| Genomespace | Centralized web application that provides data format transformations and facilitates connections with other bioinformatics tools | Web browser | LGPL | Broad Institute, collaborative project |
| GENtle | An equivalent to the proprietaryVector NTI, a tool to analyze and editDNA sequence files | Linux,macOS,Windows | GPL | Magnus Manske |
| gget | Efficient querying of genomic reference databases includingUniProt,National Center for Biotechnology Information, andEnsembl genome database project | Linux,macOS,Windows | BSD | Laura Luebbert andLior Pachter |
| GROMACS | Molecular dynamics package mainly designed for simulations of proteins, lipids and nucleic acids. | Linux,macOS,Windows | Common Public 1.0 | GenoViz |
| Integrated Genome Browser | Java-based desktopgenome browser | Linux,macOS,Windows | Common Public 1.0 | GenoViz |
| InterMine | Extensive data warehouse system for the analysis and integration of biological datasets written in Java and JavaScript | Cross-platform | LGPL | University of Cambridge |
| LabKey Server | Software platform, allows organizations to integrate, analyze, and share complex biomedical data | Linux,macOS,Windows | Apache | LabKey Software Foundation |
| LAMMPS | Molecular dynamics program written inC++ | Linux,macOS,Windows | Apache | Sandia National Laboratories. |
| mothur | Software for analysis of16S rRNA gene amplicon sequence data | Linux,macOS,Windows | GPL | University of Michigan |
| Nextflow | A workflow management system used for building and running scalable and reproducible bioinformatics pipelines, especially in cloud and high-performance computing environments. | Linux,macOS,Windows | Apache License 2.0 | Nextflow Team[6] |
| PathVisio | Desktop software for drawing, analyzing, and visualizing biological pathways | Linux,macOS,Windows | Apache 2.0 | Maastricht University |
| Orange | Component-baseddata mining andmachine learning software suite written in C++, featuring a visual programming front-end forexploratory data analysis andinteractive visualization, andPython bindings and libraries for scripting | Linux,macOS,Windows | GPL | University of Ljubljana |
| SAMtools | Utilities for interacting with high-throughput sequencing data and alignments in sam/bam format | Unix/Linux | MIT | Collaborative project |
| SOAP Suite | Suite of tools for assembly, alignment, and analysis of short readnext generation sequencing data | Unix/Linux,macOS | GPL | BGI |
| Staden Package | Sequence assembly, editing, and analysis, mainly consisting of gap4, gap5, and spin. Written in C, C++, Fortran and Tcl. | Linux,macOS,Windows | BSD | Wellcome Trust Sanger Institute,Medical Research Council |
| Taverna workbench | Tool to design and execute workflows | Linux,macOS,Windows | LGPL | myGrid |
| Tracer | Open-source eBPF-based observability client for monitoring performance and resource usage in bioinformatics workflows. | Linux | Custom license (see GitHub) | Tracer ProjectGitHub |
| T-REX (web server) | Inference, validation and visualization of phylogenetic trees and phylogenetic networks | Web browser,Windows | GNU (GPL) v3 | Université du Québec à Montréal[7] |
| UGENE | Integrated bioinformatics tools, written inC++ (Qt) | Linux,macOS,Windows | GPL 2 | Unipro |
| Unipept | Metaproteomics biodiversity analysis written in Ruby and JavaScript | Web browser | MIT | Ghent University |
| VOTCA | A Coarse-grained modeling package for molecular dynamics, written in C++, Perl, BASH | Linux,macOS,Windows, any other Unix variety | Apache License 2.0 | Max Planck Institute for Polymer Research |