Testosterone , the base androgen of most androgen esters.This is alist ofandrogen esters , includingesters (as well asethers ) ofnatural androgens liketestosterone anddihydrotestosterone (DHT) andsynthetic anabolic–androgenic steroids (AAS) likenandrolone (19-nortestosterone).
Esters of natural AAS [ edit ] Testosterone esters [ edit ] Many esters of testosterone have been marketed, including the following major esters:[ 1] [ 2]
Testosterone caproate (component ofOmnadren andTriormon Depositum )Testosterone cypionate (Depo-Testosterone, numerous others)Testosterone decanoate (component ofSustanon 250 )Testosterone enanthate (Delatestryl, numerous others) (component ofTestoviron Depot )Testosterone isobutyrate (Agovirin-Depot, Perandren M, Testocryst, Virex-Cryst; component ofFemandren M/Folivirin )Testosterone isocaproate (component ofOmnadren ,Sustanon 100 , andSustanon 250 )Testosterone phenylpropionate (component ofOmnadren ,Sustanon 100 , andSustanon 250 )Testosterone propionate (Testoviron, numerous others) (component ofOmnadren ,Sustanon 100 ,Sustanon 250 , andTestoviron Depot )Testosterone undecanoate (Aveed, Andriol, Nebido, Jatenzo, numerous others)And the following less commonly used esters:[ 1] [ 2]
Testosterone acetate (Aceto-Sterandryl, Aceto-Testoviron, Amolisin, Androtest A, Deposteron, Farmatest, Perandrone A)Testosterone cyclohexylpropionate (Andromar, Femolone, Telipex Retard; component ofTrioestrine Retard )Testosterone enantate benzilic acid hydrazone (component ofClimacteron )Testosterone furoate (Furotest)Testosterone hexahydrobenzoate (Sterandryl Retard; component ofTrinestril AP )Testosterone hexahydrobenzylcarbonate (Lontanyl)Testosterone hexyloxyphenylpropionate (Andradurin)Testosterone ketolaurate (Androdurin; component ofTestosid-Depot andKlimanosid R-Depot )Testosterone nicotinate (Bolfortan, Linobol)Testosterone phenylacetate (Perandren, Androject)Testosterone phosphate (Telipex Aquosum)Testosterone undecylenate (component ofDurasteron andTriolandren )Testosterone valerate (component ofDeposterona andTriolandren )[ 3] The following major testosterone ester has not been marketed:[ 1] [ 2]
Testosterone buciclate (20 Aet-1, CDB-1781) – a very long-acting testosterone ester that was under development but ultimately did not reach the market[ 4] [ 5] And the following less commonly known testosterone esters have also not been marketed:[ 1] [ 2]
Dihydrotestosterone esters [ edit ] Several esters ofdihydrotestosterone (DHT;androstanolone, stanolone ) have also been marketed, including the following:[ 8] [ 9]
The following esters of DHT have not been marketed:[ 8] [ 9]
Testifenon (chlorphenacyl DHT ester) is anitrogen mustard ester of DHT that was developed as acytostatic antineoplastic agent but was never marketed.[ 10]
Esters of other natural AAS [ edit ] The following esters of other natural AAS have been marketed:
And the following have not been marketed:
Sturamustine is anitrosourea ester ofdehydroepiandrosterone (DHEA) that was developed as acytostatic antineoplastic agent but was never marketed.[ 12] [ 13]
Ethers of natural AAS [ edit ] Although not esters, the following ethers of natural AAS have been marketed as well:
And the following have not been marketed:
Esters of synthetic AAS [ edit ] Many esters of the synthetic AASnandrolone (19-nortestosterone) have been marketed, including the following major esters:[ 14] [ 15] [ 16]
And the following less commonly used esters:[ 14] [ 15] [ 16]
Nandrolone caproate (Anabolin Depot)Nandrolone cyclohexanecarboxylate (Nor-Durandron, Norlongandron)Nandrolone cyclohexylpropionate (Andol, Fherbolico, Megabolin, Megabolin Retar, Pluropon, Proteron-Depot, Sanabolicum)Nandrolone cypionate (Anabo, Depo-Nortestonate, Dynabol, Nortestrionate, Pluropon, Sterocrinolo)Nandrolone furylpropionate (Demelon)Nandrolone hexyloxyphenylpropionate (Anador, Anadur, Anadurine)Nandrolone hydrogen succinate (Anabolico, Menidrabol)Nandrolone laurate (Clinibolin, Fortadex, Laurabolin)Nandrolone propionate (Anabolicus, Nor-Anabol, Nortesto, Norbyol 19, Pondus, Testobolin)Nandrolone sulfate (Keratyl, Nandrol, Nandain, Colirio Ocul Nandrol)Nandrolone undecanoate (Dynabolin, Dynabolon, Psychobolan)The following nandrolone esters exist but were never marketed:
LS-1727 is anitroso carbamate ester of nandrolone that was developed as acytostatic antineoplastic agent but was never marketed.[ 19]
A few esters of the synthetic AAStrenbolone have been marketed, including the following esters:
The following trenbolone esters exist but were never marketed:
Esters of other synthetic AAS [ edit ] Many esters of other synthetic AAS have been marketed as well, including the following:
Bolandiol dipropionate (Anabiol, Storinal)Bolazine capronate (bolazine caproate) (Roxilon Inject)Boldenone acetate (Equilon 100)Boldenone cypionate (Equilon 100)Boldenone propionate (Equilon 100)Boldenone undecylenate (boldenone undecenoate) (Boldane, Equilon 100, Equipoise, Parenabol, Vebonol, others)Clostebol acetate (Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit)Clostebol caproate (Macrobin-Depot)Clostebol propionate (Yonchlon)Drostanolone propionate (Masteron, Drolban, Masteril, Mastisol, Metormon, Permastril)Metenolone acetate (Primobolan, Primobolan S, Primonabol, Nibal)Metenolone enantate (Primobolan Depot)Norclostebol acetate (Anabol 4-19)Oxabolone cipionate (Steranabol Depo, Steranabol Ritardo)Propetandrol (norethandrolone 3β-propionate) (Solevar)Stenbolone acetate (Stenobolone, Anatrofin)Whereas the following have not been marketed:
Ethers of synthetic AAS [ edit ] Although not esters, the following ethers of synthetic AAS have been marketed as well:
And the following have not been marketed:
^a b c d Index Nominum 2000: International Drug Directory ISBN 978-3-88763-075-1 . Retrieved29 May 2012 .^a b c d e f g J. Elks (14 November 2014).The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies ISBN 978-1-4757-2085-3 ^ William Llewellyn (2011).Anabolics ISBN 978-0-9828280-1-4 ^ E. Nieschlag; H. M. Behre (1 April 2004).Testosterone: Action, Deficiency, Substitution ISBN 978-1-139-45221-2 ^ Shalender Bhasin (13 February 1996).Pharmacology, Biology, and Clinical Applications of Androgens: Current Status and Future Prospects ISBN 978-0-471-13320-9 ^ "R&D Research" .www.evestra.com . Archived fromthe original on 2017-09-29.^ Ahmed G, Elger W, Meece F, Nair HB, Schneider B, Wyrwa R, Nickisch K (October 2017). "A prodrug design for improved oral absorption and reduced hepatic interaction".Bioorg. Med. Chem .25 (20):5569– 5575.doi :10.1016/j.bmc.2017.08.027 .PMID 28886996 . ^a b J. Elks (14 November 2014).The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies ISBN 978-1-4757-2085-3 ^a b I.K. Morton; Judith M. Hall (6 December 2012).Concise Dictionary of Pharmacological Agents: Properties and Synonyms ISBN 978-94-011-4439-1 ^ Lagova ND, Sof'ina ZP, Shkodinskaia EN, Kurdiumova KN, Valueva IM (1988). "[The antineoplastic activity of testiphenon]".Vopr Onkol (in Russian).34 (11):1363– 8.PMID 3201773 . ^ George W.A Milne (8 May 2018).Drugs: Synonyms and Properties: Synonyms and Properties ISBN 978-1-351-78989-9 ^ J. Elks (14 November 2014).The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies ISBN 978-1-4757-2085-3 ^ Chavis C, de Gourcy C, Borgna JL, Imbach JL (1982). "New steroidal nitrosoureas".Steroids .39 (2):129– 47.doi :10.1016/0039-128x(82)90081-2 .PMID 7071885 .S2CID 21042994 . ^a b J. Elks (14 November 2014).The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies ISBN 978-1-4757-2085-3 ^a b Index Nominum 2000: International Drug Directory 716– 717.ISBN 978-3-88763-075-1 ^a b I.K. Morton; Judith M. Hall (6 December 2012).Concise Dictionary of Pharmacological Agents: Properties and Synonyms ISBN 978-94-011-4439-1 ^ Lerner, Leonard J.; Holthaus, Fred J.; Thompson, Charles R. (1959). "A myotrophic agent and gonadotrophin inhibitor, 19-nortestosterone-17-benzoate".Endocrinology .64 (6):1010– 1016.doi :10.1210/endo-64-6-1010 .ISSN 0013-7227 .PMID 13652918 . ^ Boschann, H. -W. (1955). "Cytologische Untersuchungen über die Wirkung von Androgenen am atrophischen Vaginalepithel in Abhängigkeit von Dosierung und Applikationsart".Archiv für Gynäkologie .187 (1):39– 64.doi :10.1007/BF00985845 .ISSN 0003-9128 .PMID 13303168 .S2CID 30443548 . ^ Hartley-Asp B, Wilkinson R, Venitt S, Harrap KR (1981). "Studies on the mechanism of action of LS 1727, a nitrosocarbamate of 19-nortestosterone".Acta Pharmacol Toxicol (Copenh) .48 (2):129– 38.doi :10.1111/j.1600-0773.1981.tb01598.x .PMID 6167141 .
Androgens AAS Tooltip anabolic–androgenic steroid )
Antiandrogens
AR Tooltip Androgen receptor antagonists Steroidogenesis
Antigonadotropins D2 receptor antagonists (prolactin releasers ) (e.g.,domperidone ,metoclopramide ,risperidone ,haloperidol ,chlorpromazine ,sulpiride )Estrogens (e.g.,bifluranol ,diethylstilbestrol ,estradiol ,estradiol esters ,ethinylestradiol ,ethinylestradiol sulfonate ,paroxypropione )GnRH agonists (e.g.,leuprorelin )GnRH antagonists (e.g.,cetrorelix )Progestogens (incl.,chlormadinone acetate ,cyproterone acetate ,hydroxyprogesterone caproate ,gestonorone caproate ,medroxyprogesterone acetate ,megestrol acetate )Others
