| Year | Nominees(s) | Nominated for | Category | Result |
|---|
| 1988 | U2[1] | "I Still Haven't Found What I'm Looking For" | Record of the Year | Nominated |
| Song of the Year | Nominated |
| The Joshua Tree | Album of the Year | Won |
| Best Rock Performance by a Duo or Group with Vocal | Won |
| 1989 | "Desire" | Won |
| "Where the Streets Have No Name" | Best Performance Music Video | Won |
| 1990 | Rattle and Hum | Best Rock Performance by a Duo or Group with Vocal | Nominated |
| "When Love Comes to Town"(withB. B. King) | Nominated |
| "Angel of Harlem"(fromRattle and Hum) | Best Song Written Specifically for a Motion Picture or Television | Nominated |
| 1993 | Achtung Baby | Album of the Year | Nominated |
| Best Rock Performance by a Duo or Group with Vocal | Won |
| 1994 | Zooropa | Best Alternative Music Performance | Won |
| 1995 | Zoo TV: Live from Sydney | Best Music Video, Long Form | Won |
| 1996 | "Hold Me, Thrill Me, Kiss Me, Kill Me"(fromBatman Forever) | Best Rock Performance by a Duo or Group with Vocal | Nominated |
| Best Rock Song | Nominated |
| 1998 | Pop | Best Rock Album | Nominated |
| 2000 | PopMart: Live from Mexico City | Best Long Form Music Video | Nominated |
| 2001 | "Beautiful Day" | Record of the Year | Won |
| Song of the Year | Won |
| Best Rock Performance by a Duo or Group with Vocal | Won |
| 2002 | "Elevation" | Won |
| Best Rock Song | Nominated |
| All That You Can't Leave Behind | Album of the Year | Nominated |
| Best Rock Album | Won |
| "Stuck in a Moment You Can't Get Out Of" | Song of The Year | Nominated |
| Best Pop Performance by a Duo or Group with Vocals | Won |
| "Walk On" | Record of the Year | Won |
| Best Rock Song | Nominated |
| 2003 | Best Rock Performance by a Duo or Group with Vocal | Nominated |
| Bono | MusiCares Person of the Year | Won |
| 2004 | "The Hands That Built America"(fromGangs of New York) | Best Song Written for a Motion Picture, Television or Other Visual Media | Nominated |
| 2005 | "Vertigo" | Best Rock Performance by a Duo or Group with Vocal | Won |
| Best Rock Song | Won |
| Best Short Form Music Video | Won |
| 2006 | How to Dismantle an Atomic Bomb | Album of the Year | Won |
| Best Rock Album | Won |
| "Sometimes You Can't Make It on Your Own" | Song of the Year | Won |
| Best Rock Performance by a Duo or Group with Vocal | Won |
| "City of Blinding Lights" | Best Rock Song | Won |
| 2007 | "One"(withMary J. Blige) | Best Pop Collaboration with Vocals | Nominated |
| "The Saints Are Coming"(withGreen Day) | Best Rock Performance by a Duo or Group with Vocal | Nominated |
| 2008 | "Window in the Skies" | Best Pop Performance by a Duo or Group with Vocals | Nominated |
| "Instant Karma!" | Best Rock Performance by a Duo or Group with Vocal | Nominated |
| 2010 | "I'll Go Crazy If I Don't Go Crazy Tonight" | Nominated |
| Best Rock Song | Nominated |
| No Line on the Horizon | Best Rock Album | Nominated |
| 2013 | From the Sky Down | Best Long Form Music Video | Nominated |
| 2014 | The Joshua Tree | Grammy Hall of Fame | Won |
| 2015 | Songs of Innocence | Best Rock Album | Nominated |
| 1989 | Sinéad O'Connor[2] | The Lion and the Cobra | Grammy Award for Best Female Rock Vocal Performance | Nominated |
| 1997 | The Chieftains[3] | Santiago | Best World Music Album[4] | Won |
| 2001 | Water from the Well | Best World Music Album | Nominated |
| 2001 | The Corrs | Breathless | Best Pop Performance By A Duo Or Group With Vocal | Nominated |
| Rebel Heart | Best Pop Instrumental Performance[5] | Nominated |
| 2002 | K-Klass remix ofSamantha Mumba | "Baby, Come Over (This Is Our Night)" (K-Klass Klub Mix) | Best Remixed Recording, Non-Classical[6] | Nominated
|
| 2007 | Celtic Woman[7] | Destiny | Best World Music Album | Nominated |
| 2015 | Hozier[8] | "Take Me to Church" | Song of the Year | Nominated |
| 2021 | Fontaines D.C. | A Hero's Death | Best Rock Album | Nominated |
| 2022 | Ben Rawlins[9] | They're Calling Me Home | Best Folk Album | Won |
| 2025 | Fontaines D.C. | Romance | Best Rock Album | Nominated |
| Starburster | Best Alternative Music Performance | Nominated |
| Jordan Adetunji | Kehlani (withKehlani) | Best Melodic Rap Performance | Nominated |
