At 16, Edelstein was a cheerleader for theNew Jersey Generals. Edelstein participated in a protest against poor working conditions. She said she felt they were treated "like hookers" and helped organize a cheerleader walkout.[5]
While living in New York, she became involved in theclub scene (known there only as "Lisa E") with "celebutant"James St. James, who briefly refers to Edelstein in his 1999 bookDisco Bloodbath. She caused enough of a stir in the community to be dubbed New York City’s "Queen of the Night" byMaureen Dowd in a 1986 article ofThe New York Times entitled "Lisa In Wonderland."[6]
In response to the growingAIDS crisis of the 1980s, Edelstein wrote, composed and starred in an original musical calledPositive Me which she performed atLa MaMa Experimental Theatre Club in New York City, receiving many accolades.[7] She followed that with a short stint hosting MTV’sAwake on the Wild Side in 1990, then began working in earnest as an actress. She got her SAG card appearing as a backstage make-up artist inOliver Stone'sJim Morrison biographyThe Doors, and then landed a quick series of guest roles on several popular comedies, includingMad About You,Wings,The Larry Sanders Show, andSports Night, where she played a sports reporter who claimed to be a former lover ofJosh Charles' character whom he did not remember. Perhaps most famous from this time was her appearances onSeinfeld, where she playedGeorge Costanza's girlfriend in the episodes "The Mango" and "The Masseuse."
From 2004 to 2011, Edelstein portrayedLisa Cuddy, theDean of Medicine at Princeton-Plainsboro Teaching Hospital and frequent adversary, friend, and eventual girlfriend of title characterGregory House (Hugh Laurie) onFox's TV seriesHouse. Edelstein has often spoken fondly of her experiences on the show and fellow cast and crew, especially her friendship and strong working relationship with Laurie.
In May 2011, Edelstein announced that she would not return for theeighth and final season ofHouse.[8] Starting in June 2011, she joined the cast ofThe Good Wife, where she played lawyer Celeste Serrano.[9] She guest-starred inScandal in 2013, and later three episodes of the ABC seriesCastle.
In 2014, Edelstein landed the lead role of Abby McCarthy in theBravo seriesGirlfriends' Guide to Divorce, an hour-long dramedy loosely based on the book series byVicki Iovine focusing on the lives of newly divorced, mid-life women.[10] It ran for five seasons in which she got to expand her creative participation by becoming a producer, writer, and director on the series.[11][12]
In 2018, Edelstein joined the cast ofABC'sThe Good Doctor in season two as Dr. Marina Blaize in a recurring role.[13] This reunited her withHouse creatorDavid Shore as well as withRichard Schiff, who played her father onRelativity.
Edelstein then joined the award winningThe Kominsky Method, aNetflix series that debuted in November 2018, playing the drug-addled daughter ofAlan Arkin and working alongside such actors such asMichael Douglas,Paul Reiser andChuck Lorre. During that time she also reunited withRob Lowe, playing his ex-wife Gwyneth Morgan, and mother of TK Strand (Ronen Rubenstein) on the ABC drama series9-1-1: Lone Star.[14] She played a Holocaust survivor and adopted mother in the Canadian indigenous TV dramaLittle Bird, which was nominated for 19 Canadian Screen Awards.
Edelstein is a supporter ofBest Friends Animal Society, of which she is an ambassador. She supports human rights organizations and is a patron of the arts. She has appeared in numerous magazines, including the September 2010 cover ofH magazine.[15] She posed forPETA in an ad promoting vegetarianism, a diet she has followed for most of her life.[16]
During theCOVID-19 pandemic in 2020, Edelstein began to sketch and paint. She began working with magic marker, and at the suggestion of her artist husband Robert Russell switched to watercolor as the size of each piece grew. Edelstein's portfolio is inspired by old family photographs that are "unintended moments, telling unintended truths".[citation needed]
^Iovine, Vicki (2001).The girlfriend's guide to getting your groove back : loving your family without losing your mind (1st ed.). New York, N.Y.: Berkley Pub. Group.ISBN0-399-52630-7.OCLC45493142.
^"Lisa Edelstein".Bravo TV Official Site. September 2, 2014. RetrievedFebruary 24, 2023.She has penned two episodes of the series, including episode #303, "Rule #187: You Are What You Eat, So… Chow Down" and episode #203, "Rule #8: Timing Is Everything," the latter which she wrote with creator and executive producer Marti Noxon.
^abcde"Lisa Edelstein (visual voices guide)". Behind The Voice Actors. RetrievedNovember 26, 2023. A green check mark indicates that a role has been confirmed using a screenshot (or collage of screenshots) of a title's list of voice actors and their respective characters found in its credits or other reliable sources of information.