| Names | |
|---|---|
| IUPAC name (2S)-4′,7-Dihydroxyflavan-4-one | |
| Systematic IUPAC name (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one | |
| Identifiers | |
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3D model (JSmol) | |
| ChEBI | |
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| Properties | |
| C15H12O4 | |
| Molar mass | 256.257 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Liquiritigenin is aflavanone that was isolated fromGlycyrrhiza uralensis, and is found in a variety of plants of theGlycyrrhiza genus, includingGlycyrrhiza glabra (licorice).[1] It is anestrogenic compound which acts as a selectiveagonist of theERβ subtype of theestrogen receptor (ER),[2] though it is also reported to act as anERαpartial agonist at sufficient concentrations.[3] It also has acholeretic effect.[1]
Liquiritigenin,NADPH:oxygen oxidoreductase (hydroxylating, aryl migration) is anenzyme that uses liquiritigenin, O2, NADPH and H+ to produce2,7,4'-trihydroxyisoflavanone, H2O, and NADP+.