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LPK-26

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
LPK-26
Identifiers
  • 2-(3,4-dichlorophenyl)-N-[(2S)-1-(2,5-dihydropyrrol-1-yl)-3-methylbutan-2-yl]-N-methylacetamide
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
ECHA InfoCard100.161.432Edit this at Wikidata
Chemical and physical data
FormulaC18H24Cl2N2O
Molar mass355.30 g·mol−1
3D model (JSmol)
  • CC(C)[C@@H](CN1CC=CC1)N(C)C(=O)CC2=CC(=C(C=C2)Cl)Cl
  • InChI=1S/C18H24Cl2N2O/c1-13(2)17(12-22-8-4-5-9-22)21(3)18(23)11-14-6-7-15(19)16(20)10-14/h4-7,10,13,17H,8-9,11-12H2,1-3H3/t17-/m1/s1 ☒N
  • Key:QFAIAMMFKKYCTL-QGZVFWFLSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

LPK-26 is a potent and selectiveκ-opioidagonist, and hasanalgesic effects.[1]

See also

[edit]

References

[edit]
  1. ^Tao YM, Li QL, Zhang CF, Xu XJ, Chen J, Ju YW, Chi ZQ, Long YQ, Liu JG (April 2008). "LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential".European Journal of Pharmacology.584 (2–3):306–11.doi:10.1016/j.ejphar.2008.02.028.PMID 18353307.
μ-opioid
(MOR)
Agonists
(abridged;
full list)
Antagonists
δ-opioid
(DOR)
Agonists
Antagonists
κ-opioid
(KOR)
Agonists
Antagonists
Nociceptin
(NOP)
Agonists
Antagonists
Others


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