This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.[5]
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Im DS, Heise CE, Harding MA, et al. (2000). "Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate".Mol. Pharmacol.57 (4):753–9.doi:10.1124/mol.57.4.753.PMID10727522.
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Cremers B, Flesch M, Kostenis E, et al. (2003). "Modulation of myocardial contractility by lysophosphatidic acid (LPA)".J. Mol. Cell. Cardiol.35 (1):71–80.doi:10.1016/S0022-2828(02)00279-1.PMID12623301.
Fujita T, Miyamoto S, Onoyama I, et al. (2003). "Expression of lysophosphatidic acid receptors and vascular endothelial growth factor mediating lysophosphatidic acid in the development of human ovarian cancer".Cancer Lett.192 (2):161–9.doi:10.1016/S0304-3835(02)00713-9.PMID12668280.
Xing Y, Ganji SH, Noh JW, Kamanna VS (2005). "Cell density-dependent expression of EDG family receptors and mesangial cell proliferation: role in lysophosphatidic acid-mediated cell growth".Am. J. Physiol. Renal Physiol.287 (6): F1250–7.doi:10.1152/ajprenal.00342.2003.PMID15292052.
"Lysophospholipid Receptors: LPA3".IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived fromthe original on 2016-03-03. Retrieved2008-12-05.