JWH-196

Legal status
Legal status	UK: Class B US: Schedule I
Identifiers
IUPAC name 2-Methyl-3-(1-naphthalenylmethyl)-1-pentyl-1H-Indole
CAS Number	619294-41-6
ChemSpider	35303441
UNII	M88JKX4UVV
Chemical and physical data
Formula	C25H27N
Molar mass	341.498 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCCCn1c(c(c2c1cccc2)Cc3cccc4c3cccc4)C
InChI InChI=1S/C25H27N/c1-3-4-9-17-26-19(2)24(23-15-7-8-16-25(23)26)18-21-13-10-12-20-11-5-6-14-22(20)21/h5-8,10-16H,3-4,9,17-18H2,1-2H3 Key:LDTJKFUAZQDSQS-UHFFFAOYSA-N

JWH-196 is a syntheticcannabinoid receptor ligand from thenaphthylmethylindole family. It is theindole 2-methyl derivative of related compoundJWH-175, and the carbonyl reduced analog ofJWH-007. The binding affinity of JWH-196 for the CB₁ receptor is reported as K_i = 151 ± 18 nM.^[1]

In the United States, all CB₁ receptor agonists of the 3-(1-naphthylmethane)indole class such as JWH-196 areSchedule I Controlled Substances.^[2]

• JWH-007
• JWH-175

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