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| Formula | C27H27NO |
| Molar mass | 381.519 g·mol−1 |
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JWH-147 is ananalgesic drug used in scientific research, which acts as acannabinoidagonist at both theCB1 andCB2receptors. It is somewhat selective for the CB2 subtype, with aKi of 11.0 nM at CB1 vs 7.1 nM at CB2.[1] It was discovered and named after the renowned professor of organic chemistryJohn W. Huffman.
In the United States, CB1 receptor agonists of the 3-(1-naphthoyl)pyrrole class such as JWH-147 areSchedule I Controlled Substances.[2]
JWH-147 was banned in Sweden on 1 October 2010 as harmful to health, after being identified as an ingredient in "herbal"synthetic cannabis products.[3][4]
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