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| Formula | C23H21NO |
| Molar mass | 327.427 g·mol−1 |
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JWH-120 is a synthetic cannabimimetic that was discovered byJohn W. Huffman. It is theN-propyl analog ofJWH-122. It is a potent and selective ligand for theCB2 receptor, but a weaker ligand for theCB1 receptor. It has a binding affinity ofKi = 6.1 ± 0.7 nM at the CB2 subtype and 173 times selectivity over the CB1 subtype.[1]
In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as JWH-120 areSchedule I Controlled Substances.[2]
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